ID   ACT1_ECHGR              Reviewed;         375 AA.
AC   P35432;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Actin-1;
GN   Name=ACTI;
OS   Echinococcus granulosus (Hydatid tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;
OC   Echinococcus granulosus group.
OX   NCBI_TaxID=6210;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8232413; DOI=10.1016/0166-6851(93)90132-h;
RA   da Silva C.M., Ferreira H.B., Picon M., Gorfinkiel N., Ehrlich R., Zaha A.;
RT   "Molecular cloning and characterization of actin genes from Echinococcus
RT   granulosus.";
RL   Mol. Biochem. Parasitol. 60:209-220(1993).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; L07773; AAC80573.1; -; Genomic_DNA.
DR   AlphaFoldDB; P35432; -.
DR   SMR; P35432; -.
DR   PRIDE; P35432; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..375
FT                   /note="Actin-1"
FT                   /id="PRO_0000088933"
SQ   SEQUENCE   375 AA;  41828 MW;  AFA3ED3A3EC9C45A CRC64;
     MAEEITPLVV DNGSGMCKAG FAGDDSPRAV FPSLVGRPRQ QSIMVGMGNK DSYVGDEAQS
     KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT
     QIMFETFNVR AMYVAIQAVL SLYASGRTTG IVLDSGDGVS HTVPIYEGYA LPHAILRLDL
     AGRDLTDWLT KLLTERGYAF TTTAELEIVR DIKEKLCYVA LDFENEMATA ATSSSLEKTY
     ELPDGQVITV GNERFRCPEA LYQPSFLGLE CNGIHETTYN SIMKCDLDIR KDLYSNVVLS
     GGSTMYPGIA DRMNKDLTAL APTTMKIKII APPERKYSVW IGGSILASLS TFQQMWITKQ
     EYDESGPSIV HRKCF