ID   ACT1_HALRO              Reviewed;         378 AA.
AC   P53460;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Actin, muscle 1A;
GN   Name=MA1A;
OS   Halocynthia roretzi (Sea squirt) (Cynthia roretzi).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Stolidobranchia;
OC   Pyuridae; Halocynthia.
OX   NCBI_TaxID=7729;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Gonad;
RX   PubMed=7781891; DOI=10.1006/dbio.1995.1161;
RA   Kusakabe T., Hikosaka A., Satoh N.;
RT   "Coexpression and promoter function in two muscle actin gene complexes of
RT   different structural organization in the ascidian Halocynthia roretzi.";
RL   Dev. Biol. 169:461-472(1995).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- FUNCTION: Multiple isoforms are involved in various cellular functions
CC       such as cytoskeleton structure, cell mobility, chromosome movement and
CC       muscle contraction.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; D29014; BAA06100.1; -; Genomic_DNA.
DR   AlphaFoldDB; P53460; -.
DR   SMR; P53460; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Muscle protein; Nucleotide-binding.
FT   CHAIN           1..378
FT                   /note="Actin, muscle 1A"
FT                   /id="PRO_0000088946"
SQ   SEQUENCE   378 AA;  42045 MW;  015E51B65F57C816 CRC64;
     MSDGEEDQTA IVCDNGSGLV KSGFAGDDAP RAVFPSTVGR PRHQGVMVGM GQKDSYVGDE
     AQSKRGILTL KYPIEHGIIT NWDDMEKIWH HTFYNELRVA PEEHPTLLTE APLNPKANRE
     KMTQIMFETF NVPAMYVAIQ AVLSLYASGR TTGIVLDSGD GVSHNVPIYE GYALPHAIAR
     LDLAGRDLTD YLMKILTERG YSFVTTAERE IVRDIKEKLC YVALDFEQEM ATAASSTSLE
     KSYELPDGQV ITIGNERFRC PETLFQPSFI GMESAGIHET TYNSIMKCDI DIRKDLYANN
     VLSGGSTMYP GIADRMQKEI TALAPSTMKI KIIAPPERKY SVWIGGSILA SLSTFQQMWI
     TKQEYDEAGP SIVHRKCF