ACT1_HELTB
ID ACT1_HELTB Reviewed; 376 AA.
AC P69003; P53462;
DT 01-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Actin CyI, cytoplasmic;
DE Flags: Precursor;
OS Heliocidaris tuberculata (Sea urchin).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC Euechinoidea; Echinacea; Camarodonta; Echinidea; Echinometridae;
OC Heliocidaris.
OX NCBI_TaxID=7635;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7875592; DOI=10.1016/0378-1119(94)00775-n;
RA Hahn J.-H., Kissinger J.C., Raff R.A.;
RT "Structure and evolution of CyI cytoplasmic actin-encoding genes in the
RT indirect- and direct-developing sea urchins Heliocidaris tuberculata and
RT Heliocidaris erythrogramma.";
RL Gene 153:219-224(1995).
CC -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC various types of cell motility and are ubiquitously expressed in all
CC eukaryotic cells.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR EMBL; U12272; AAA96349.1; -; Genomic_DNA.
DR EMBL; U09636; AAA96349.1; JOINED; Genomic_DNA.
DR AlphaFoldDB; P69003; -.
DR SMR; P69003; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR004001; Actin_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
DR PROSITE; PS00406; ACTINS_1; 1.
DR PROSITE; PS00432; ACTINS_2; 1.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 3: Inferred from homology;
KW Acetylation; ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT PROPEP 1..2
FT /note="Removed in mature form"
FT /evidence="ECO:0000250"
FT /id="PRO_0000000678"
FT CHAIN 3..376
FT /note="Actin CyI, cytoplasmic"
FT /id="PRO_0000000679"
FT MOD_RES 3
FT /note="N-acetylaspartate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 376 AA; 41788 MW; 396A6BD812C23BA4 CRC64;
MCDDDVAALV IDNGSGMVKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ
SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM
TQIMFETFNS PAMYVAIQAV LSLYASGRTT GIVFDSGDGV SHTVPIYEGY ALPHAILRLD
LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFEQEMST AASSSSLEKS
YELPDGQVIT IGNERFRAPE SLFQPSFLGM ESAGIHETTY NSIMKCDVDI RKDLYANTVL
SGGSTMFPGI ADRMQKEITA LAPPTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
QEYDESGPSI VHRKCF