ACT1_LUMTE
ID ACT1_LUMTE Reviewed; 376 AA.
AC P92182;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1997, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Actin-1;
DE Flags: Precursor;
GN Name=ACT1;
OS Lumbricus terrestris (Common earthworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC Oligochaeta; Crassiclitellata; Lumbricina; Lumbricidae; Lumbricinae;
OC Lumbricus.
OX NCBI_TaxID=6398;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX PubMed=8921915; DOI=10.1016/0378-1119(96)00371-x;
RA Lewke N., Weber K.;
RT "Nucleotide sequence of two actin genes of Lumbricus terrestris.";
RL Gene 178:199-200(1996).
CC -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC various types of cell motility and are ubiquitously expressed in all
CC eukaryotic cells.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR EMBL; X96515; CAA65364.1; -; Genomic_DNA.
DR EMBL; X96512; CAA65361.1; -; mRNA.
DR EMBL; X96514; CAA65363.1; -; mRNA.
DR PIR; JC5227; JC5227.
DR AlphaFoldDB; P92182; -.
DR SMR; P92182; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR004001; Actin_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
DR PROSITE; PS00406; ACTINS_1; 1.
DR PROSITE; PS00432; ACTINS_2; 1.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 2: Evidence at transcript level;
KW Acetylation; ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT PROPEP 1..2
FT /note="Removed in mature form"
FT /evidence="ECO:0000250"
FT /id="PRO_0000000692"
FT CHAIN 3..376
FT /note="Actin-1"
FT /id="PRO_0000000693"
FT MOD_RES 3
FT /note="N-acetylaspartate"
FT /evidence="ECO:0000250"
SQ SEQUENCE 376 AA; 41846 MW; D0C3D73C7F1DA0AC CRC64;
MCDEEVTALV VDNGSGMCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ
SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM
TQIMFETFNS PAMYVAIQAV LSLYASGRTT GIVLDSGDGV THTVPIYEGY ALPHAILRLD
LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFDQEMGT AASSSSLEKS
YELPDGQVIT IGNERFRCPE SMFQPAFLGM ESAGIHETTF NSIMKCDVDI RKDLYANTVM
SGGTTMFPGI ADRMQKEITS MAPSTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
QEYDESGPSI VHRKCF