ID   ACT1_LYTPI              Reviewed;         376 AA.
AC   P53465;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Actin, cytoskeletal 1;
DE   AltName: Full=LPC1;
DE   Flags: Precursor;
OS   Lytechinus pictus (Painted sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Temnopleuroida; Toxopneustidae; Lytechinus.
OX   NCBI_TaxID=7653;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=7966365; DOI=10.1007/bf00160267;
RA   Fang H., Brandhorst B.P.;
RT   "Evolution of actin gene families of sea urchins.";
RL   J. Mol. Evol. 39:347-356(1994).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton.
CC   -!- TISSUE SPECIFICITY: Expressed in several different spatial territories
CC       of the embryo.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; U09651; AAA53363.1; -; mRNA.
DR   AlphaFoldDB; P53465; -.
DR   SMR; P53465; -.
DR   PRIDE; P53465; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   PROPEP          1..2
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000000694"
FT   CHAIN           3..376
FT                   /note="Actin, cytoskeletal 1"
FT                   /id="PRO_0000000695"
FT   MOD_RES         3
FT                   /note="N-acetylaspartate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   376 AA;  41842 MW;  34F9C757A1F65C90 CRC64;
     MCDDDIAALV IDNGSGMVKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGGQAQ
     SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM
     TQIMFETFNS PAMYVAIQAV LSLYASGRTT GIVFDSGDGV SYTVPIYEGY ALPHAILRLD
     LAGRDITDYL MKILTERGYT FTTTAEREIV RDIKEKLCYV ALDFEQEMQT AASSSSLEKS
     YELPDGQVIT IGNERFRCPE ALFQPSFLGM ESAGIHETCY NSIMKCDVDI RKDLYANTVL
     SGGSTMFPGI ADRMQKEITA LAPPTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
     QEYDESGPSI VHRKCF