ID   ACT1_OXYFA              Reviewed;         357 AA.
AC   P53503;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Actin, macronuclear;
OS   Oxytricha fallax.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX   NCBI_TaxID=5944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6799836; DOI=10.1038/295430a0;
RA   Kaine B.P., Spear B.B.;
RT   "Nucleotide sequence of a macronuclear gene for actin in Oxytricha
RT   fallax.";
RL   Nature 295:430-432(1982).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- PTM: Met-1 may be removed after translation.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; J01163; AAA29394.1; -; Genomic_DNA.
DR   AlphaFoldDB; P53503; -.
DR   SMR; P53503; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..357
FT                   /note="Actin, macronuclear"
FT                   /id="PRO_0000088974"
SQ   SEQUENCE   357 AA;  39915 MW;  1F5F5C7C7A74C759 CRC64;
     MSDQQTCVID NGSGVVKAGF AGEDAPRAVF PSIVGRPKNV SALIGVDSAS EYLGDEAQQK
     RGVLKIWNHT FYVELRVQPD EHPILLTEAP LSPKTNREKM TQIIFETFNL PALYVAIQAV
     LSLYSRGRTT GIVCDAGDGL THTVPIYEGF SIPHAVSTIQ LAGRDLTTFL AKLFTERGYN
     FTSSAELEIV RDIKEKLCFL ALNYESALKQ SHDSSQFEKN YELPHGKVIT IGSERFRCPE
     YLFKPLEMNG RELDSIQDLT YKSIQECDVD VRRDLYQNII LSGGTTMYEG IGERLLKEIE
     NRAPKSINVK VIASPDRRFA VWRGGSTLTS LSTFASMWIT KEDYDENGAS IVHRKCI