ID   ACT1_PHYIN              Reviewed;         376 AA.
AC   P22131;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Actin-1;
GN   Name=ACTA;
OS   Phytophthora infestans (Potato late blight agent) (Botrytis infestans).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4787;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2055461; DOI=10.1016/0378-1119(91)90355-f;
RA   Unkles S.E., Moon R.P., Hawkins A.R., Duncan J.M., Kinghorn J.R.;
RT   "Actin in the oomycetous fungus Phytophthora infestans is the product of
RT   several genes.";
RL   Gene 100:105-112(1991).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- TISSUE SPECIFICITY: ACTA and ACTB are actively transcribed in mycelium,
CC       sporangia and germinating cysts but only at a low level in the case of
CC       ACTB.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; M59715; AAA33749.1; -; Genomic_DNA.
DR   PIR; JE0414; JE0414.
DR   AlphaFoldDB; P22131; -.
DR   SMR; P22131; -.
DR   PRIDE; P22131; -.
DR   VEuPathDB; FungiDB:PITG_15117; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..376
FT                   /note="Actin-1"
FT                   /id="PRO_0000088984"
SQ   SEQUENCE   376 AA;  41882 MW;  314CD9140F2B610F CRC64;
     MADDDVQALV VDNGSGMCKA GFAGDDAPRA VFPSIVGRPK HLGIMVGMDQ KDAYVGDEAQ
     SKRGVLTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANRERM
     TQIMFETFNV PAMYVNIQAV LSLYASGRTT GCVLDSGDGV SHTVPIYEGY ALPHAIVRLD
     LAGRDLTDYM MKILTERGYS FTTTAEREIV RDIKEKLTYI ALDFDQEMKT AAESSGLEKS
     YELPDGNVIV IGNERFRTPE VLFQPSLIGK EASGIHECTF QTIMKCDVDI RKDLYCNIVL
     SGGTTMYPGI GERMTKELTA LAPSTMKIKV VAPPERKYSV WIGGSIQSSL STFQQMWISK
     AEYDESGPSI VHRKCF