ID   ACT1_PODCA              Reviewed;         376 AA.
AC   P41112;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Actin-1/2;
GN   Name=ACTIA;
GN   and
GN   Name=ACTIIB;
OS   Podocoryna carnea (Hydrozoan).
OC   Eukaryota; Metazoa; Cnidaria; Hydrozoa; Hydroidolina; Anthoathecata;
OC   Filifera; Hydractiniidae; Podocoryna.
OX   NCBI_TaxID=6096;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8104847; DOI=10.1016/0378-1119(93)90292-b;
RA   Aerne B.L., Schmid V., Schuchert P.;
RT   "Actin-encoding genes of the hydrozoan Podocoryne carnea.";
RL   Gene 131:183-192(1993).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- MISCELLANEOUS: There are at least six actin genes in Podocoryne carnea.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X69058; CAA48796.1; -; mRNA.
DR   EMBL; X69059; CAA48797.1; -; mRNA.
DR   PIR; JN0833; JN0833.
DR   AlphaFoldDB; P41112; -.
DR   SMR; P41112; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..376
FT                   /note="Actin-1/2"
FT                   /id="PRO_0000088997"
SQ   SEQUENCE   376 AA;  41767 MW;  FF42EB49B81816AC CRC64;
     MADDDVAALV VDNGSGMCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ
     SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM
     TQIMFETFNS PAMYVAIQAV LSLYASGRTT GIVLDSGDGV SHTVPIYEGY ALPHAIIRLD
     LAGRDLTDYM MKILTERGYS FTTTAEREIV RDIKEKLAYV ALDFEQEMQT AASSSSLEKS
     YELPDGQVIT IGNERFRDPE ALFQPAFLGM ESAGIHETTY NSIMKCDVDI RKDLYANTVL
     SGGTTMFPGI ADRMQKEISS LAPPTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
     QEYDESGPSI VHRKCF