ID   ACT1_SCHCO              Reviewed;         375 AA.
AC   Q9Y702;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Actin-1;
DE   AltName: Full=Beta-actin;
GN   Name=ACT1;
OS   Schizophyllum commune (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=5334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NBRC 30496;
RA   Yamagishi K., Kimura T., Shinmoto H.;
RT   "Schizophyllum commune beta-actin mRNA.";
RL   Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=ATCC 44201 / CBS 340.81 / UVM 4-40 / 4-40;
RX   PubMed=10863093; DOI=10.1016/s0378-1119(00)00195-5;
RA   Tarkka M.T., Vasara R., Gorfer M., Raudaskoski M.;
RT   "Molecular characterization of actin genes from homobasidiomycetes: two
RT   different actin genes from Schizophyllum commune and Suillus bovinus.";
RL   Gene 251:27-35(2000).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; AB027510; BAA77815.1; -; mRNA.
DR   EMBL; AF156157; AAD38853.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9Y702; -.
DR   SMR; Q9Y702; -.
DR   OMA; FHTTAER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..375
FT                   /note="Actin-1"
FT                   /id="PRO_0000089002"
SQ   SEQUENCE   375 AA;  41618 MW;  84C84C48C980CF9D CRC64;
     MEDEVAALVI DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGVMVGMGQK DSYVGDEAQS
     KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT
     QIMFETFNAP AFYVAIQAVL SLYASGRTTG IVLDSGDGVT HTVPIYEGFA LPHAILRLDL
     AGRDLTDFLI KNLMERGYPF TTTAEREIVR DIKEKLCYVA LDFEQELQTA AQSSALEKSY
     ELPDGQVITI GNERFRAPEA LFQPAFLGLE AAGIHETTYN SIFKCDLDIR RDLYGNVVLS
     GGTTMFPGIA DRMQKELTAL SPSSMKVKIV APPERKYSVW IGGSILASLS TFQNLWCSKQ
     EYDESGPGIV HRKCF