位置:首页 > 蛋白库 > DADA_VIBA3
DADA_VIBA3
ID   DADA_VIBA3              Reviewed;         417 AA.
AC   B7VMK8;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=D-amino acid dehydrogenase {ECO:0000255|HAMAP-Rule:MF_01202};
DE            EC=1.4.99.- {ECO:0000255|HAMAP-Rule:MF_01202};
GN   Name=dadA {ECO:0000255|HAMAP-Rule:MF_01202}; OrderedLocusNames=VS_1133;
OS   Vibrio atlanticus (strain LGP32) (Vibrio splendidus (strain Mel32)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=575788;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LGP32;
RA   Mazel D., Le Roux F.;
RT   "Vibrio splendidus str. LGP32 complete genome.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Oxidative deamination of D-amino acids. {ECO:0000255|HAMAP-
CC       Rule:MF_01202}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=A + a D-alpha-amino acid + H2O = a 2-oxocarboxylate + AH2 +
CC         NH4(+); Xref=Rhea:RHEA:18125, ChEBI:CHEBI:13193, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:17499, ChEBI:CHEBI:28938, ChEBI:CHEBI:35179,
CC         ChEBI:CHEBI:59871; Evidence={ECO:0000255|HAMAP-Rule:MF_01202};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01202};
CC   -!- PATHWAY: Amino-acid degradation; D-alanine degradation; NH(3) and
CC       pyruvate from D-alanine: step 1/1.
CC   -!- SIMILARITY: Belongs to the DadA oxidoreductase family.
CC       {ECO:0000255|HAMAP-Rule:MF_01202}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FM954972; CAV18259.1; -; Genomic_DNA.
DR   RefSeq; WP_012603643.1; NC_011753.2.
DR   AlphaFoldDB; B7VMK8; -.
DR   SMR; B7VMK8; -.
DR   STRING; 575788.VS_1133; -.
DR   PRIDE; B7VMK8; -.
DR   EnsemblBacteria; CAV18259; CAV18259; VS_1133.
DR   KEGG; vsp:VS_1133; -.
DR   PATRIC; fig|575788.5.peg.2456; -.
DR   eggNOG; COG0665; Bacteria.
DR   HOGENOM; CLU_007884_9_2_6; -.
DR   OMA; FWYKEDG; -.
DR   OrthoDB; 573710at2; -.
DR   UniPathway; UPA00043; UER00498.
DR   Proteomes; UP000009100; Chromosome 1.
DR   GO; GO:0008718; F:D-amino-acid dehydrogenase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0055130; P:D-alanine catabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.50.50.60; -; 2.
DR   HAMAP; MF_01202; DadA; 1.
DR   InterPro; IPR023080; DadA.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   Pfam; PF01266; DAO; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome.
FT   CHAIN           1..417
FT                   /note="D-amino acid dehydrogenase"
FT                   /id="PRO_1000164645"
FT   BINDING         3..17
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01202"
SQ   SEQUENCE   417 AA;  45865 MW;  9A8A254DDA1E1104 CRC64;
     MEVIVIGSGV IGLTSAWYLA KEGHTVTVID RQDSSGKETS FANAGQISYG YSSPWAAPGI
     PLKAMKWLTQ EHAPLKVKPS LSPELVAWAT KMLANCNEAK YAMNKSRMLR VANFSRECLT
     HLRTSEDLAY EGRQKGTLQV FRSEKQLDAI QQDMKLLTES GIEHSLFDVD QCLSVESGLA
     DVKDKLVGGL YLPHDETGDC HQFCLTLTEK AKQLGVRFVF DTEVVSLNHQ NRAIETITTT
     QGEFKADAYV VASGSYSREL LKQVDLSIPV YPVKGYSLTL PIVNVDKSPT STVMDETYKV
     AMTRFDDRIR IAGTAELAGF DYLIPEKRKA TIDMVIKDLF PQAGDFSKAE YWTGLRPMTP
     DGTPIIGKTP IKNLFTNTGH GTLGWTMACG SGKILASVVS GSASDIKSDD LSIHRYL
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024