ACT1_STENO
ID ACT1_STENO Reviewed; 375 AA.
AC P12715;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1989, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Actin, cytoplasmic;
DE AltName: Full=Actin, macronuclear;
OS Sterkiella nova (Ciliate) (Oxytricha nova).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Sterkiella.
OX NCBI_TaxID=200597;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3141121; DOI=10.1089/dna.1.1988.7.529;
RA Greslin A.F., Loukin S.H., Oka Y., Prescott D.M.;
RT "An analysis of the macronuclear actin genes of Oxytricha.";
RL DNA 7:529-536(1988).
CC -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC various types of cell motility and are ubiquitously expressed in all
CC eukaryotic cells.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR EMBL; M22480; AAA29393.1; -; Genomic_DNA.
DR PIR; A31134; A31134.
DR AlphaFoldDB; P12715; -.
DR SMR; P12715; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR004001; Actin_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
DR PROSITE; PS00406; ACTINS_1; 1.
DR PROSITE; PS00432; ACTINS_2; 1.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT CHAIN 1..375
FT /note="Actin, cytoplasmic"
FT /id="PRO_0000088976"
SQ SEQUENCE 375 AA; 41955 MW; 1F67341597C7F1A9 CRC64;
MADKQTVVVD NGSGVVKAGF SGEDAPRAVF PSIIGRPKNV SALIGVDSAS EYIGDEAQQK
RGVLKIFYPI EHGIIKDWED MEKIWNHTFY VELRVQPDEH PVLLTEAPLN PKTNREKMTQ
IMFETFNVPA LYVAIQAVLS LYSAGRTTGI VCDAGDGVTH TVPIYEGFSI PHAVSRIQLA
GRDLTTFMAK LLTEKGYVFT SSAEMEIVRD IKEKLCFVAL DYEAAMKQSY ESTTFEKNYE
LPDGRVITIG NARFRCPEYL FKPLEMNGKE LDSIQSLTYN SIQECDVDVR RDLYQNITLS
GGTTMYEGIG ERLLKEIEAR APKSINVKVI ASPDRRFAVW RGGSTLTSLS TFASMWITKE
DYDENGASIV HRKCL