ID   ACT1_STENO              Reviewed;         375 AA.
AC   P12715;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Actin, cytoplasmic;
DE   AltName: Full=Actin, macronuclear;
OS   Sterkiella nova (Ciliate) (Oxytricha nova).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Sterkiella.
OX   NCBI_TaxID=200597;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3141121; DOI=10.1089/dna.1.1988.7.529;
RA   Greslin A.F., Loukin S.H., Oka Y., Prescott D.M.;
RT   "An analysis of the macronuclear actin genes of Oxytricha.";
RL   DNA 7:529-536(1988).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; M22480; AAA29393.1; -; Genomic_DNA.
DR   PIR; A31134; A31134.
DR   AlphaFoldDB; P12715; -.
DR   SMR; P12715; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..375
FT                   /note="Actin, cytoplasmic"
FT                   /id="PRO_0000088976"
SQ   SEQUENCE   375 AA;  41955 MW;  1F67341597C7F1A9 CRC64;
     MADKQTVVVD NGSGVVKAGF SGEDAPRAVF PSIIGRPKNV SALIGVDSAS EYIGDEAQQK
     RGVLKIFYPI EHGIIKDWED MEKIWNHTFY VELRVQPDEH PVLLTEAPLN PKTNREKMTQ
     IMFETFNVPA LYVAIQAVLS LYSAGRTTGI VCDAGDGVTH TVPIYEGFSI PHAVSRIQLA
     GRDLTTFMAK LLTEKGYVFT SSAEMEIVRD IKEKLCFVAL DYEAAMKQSY ESTTFEKNYE
     LPDGRVITIG NARFRCPEYL FKPLEMNGKE LDSIQSLTYN SIQECDVDVR RDLYQNITLS
     GGTTMYEGIG ERLLKEIEAR APKSINVKVI ASPDRRFAVW RGGSTLTSLS TFASMWITKE
     DYDENGASIV HRKCL