ID   DALD_RALSO              Reviewed;         465 AA.
AC   P58708;
DT   31-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   31-JAN-2002, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=D-arabinitol 4-dehydrogenase;
DE            EC=1.1.1.11;
GN   Name=dalD; OrderedLocusNames=RSc2129; ORFNames=RS01475;
OS   Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-arabinitol + NAD(+) = D-xylulose + H(+) + NADH;
CC         Xref=Rhea:RHEA:17921, ChEBI:CHEBI:15378, ChEBI:CHEBI:17140,
CC         ChEBI:CHEBI:18333, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.11;
CC   -!- PATHWAY: Carbohydrate metabolism; D-arabinitol metabolism.
CC   -!- SIMILARITY: Belongs to the mannitol dehydrogenase family.
CC       {ECO:0000305}.
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DR   EMBL; AL646052; CAD15836.1; -; Genomic_DNA.
DR   RefSeq; WP_011002060.1; NC_003295.1.
DR   AlphaFoldDB; P58708; -.
DR   SMR; P58708; -.
DR   STRING; 267608.RSc2129; -.
DR   PRIDE; P58708; -.
DR   EnsemblBacteria; CAD15836; CAD15836; RSc2129.
DR   GeneID; 60501642; -.
DR   KEGG; rso:RSc2129; -.
DR   PATRIC; fig|267608.8.peg.2163; -.
DR   eggNOG; COG0246; Bacteria.
DR   HOGENOM; CLU_027324_0_2_4; -.
DR   OMA; WGSENTE; -.
DR   UniPathway; UPA00380; -.
DR   Proteomes; UP000001436; Chromosome.
DR   GO; GO:0047813; F:D-arabinitol 4-dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0051161; P:arabitol metabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.1040.10; -; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR000669; Mannitol_DH.
DR   InterPro; IPR013118; Mannitol_DH_C.
DR   InterPro; IPR013131; Mannitol_DH_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
DR   PRINTS; PR00084; MTLDHDRGNASE.
DR   SUPFAM; SSF48179; SSF48179; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   NAD; Oxidoreductase; Reference proteome.
FT   CHAIN           1..465
FT                   /note="D-arabinitol 4-dehydrogenase"
FT                   /id="PRO_0000170736"
SQ   SEQUENCE   465 AA;  50630 MW;  47095425D4836342 CRC64;
     MTRSSLARAP VLLHIGAGSF HRAHQAWYLH RVNAAVPPGE RWTLTVGNIR DDMHATLAAL
     AAQQGAYTLE TVTPQGERAY ETIRSIARVL PWSADLAALI NTGADPACRI VSFTVTEGGY
     YLDEHDRLDV THPDLAADLR GARSTLYGAL AALLAERRQR GAGPLTLQSC DNLRSNGARF
     RAGMRAFLAL RGDAALLAWF DANVSCPSAM VDRITPRPTD DVRTRVHAAT GVDDRCPVMG
     ESFIQWVIED NFIAGRPAWE IAGAEIVADV HPYEEAKIRI LNATHSCIAW AGTLAGLTYI
     HEGMRDAAIY RFAYDYVTDD VIPCLTPSPL DLERYRDVVL ERFGNPYVLD TNQRVAADGF
     SKIPGFIAPT LAECFARGAD PVATAVLPAL FLGFLEGWAR GTLPYVYQDG VMDGAAARSI
     VEAPDSVAAF CSDRQLWGSL AGRDALVQAV RAGRARVEAW RAARR