ID   DALT_KLEPN              Reviewed;         425 AA.
AC   O52718;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=D-arabinitol transporter;
GN   Name=dalT;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1033-5P14 / KAY2026;
RX   PubMed=9324246; DOI=10.1128/jb.179.19.6014-6019.1997;
RA   Heuel H., Turgut S., Schmid K., Lengeler J.W.;
RT   "Substrate recognition domains as revealed by active hybrids between the D-
RT   arabinitol and ribitol transporters from Klebsiella pneumoniae.";
RL   J. Bacteriol. 179:6014-6019(1997).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC       transporter (TC 2.A.1.1) family. CsbX subfamily. {ECO:0000305}.
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DR   EMBL; AF045245; AAC26500.1; -; Genomic_DNA.
DR   RefSeq; WP_002912654.1; NZ_WYAM01000007.1.
DR   AlphaFoldDB; O52718; -.
DR   TCDB; 2.A.1.18.1; the major facilitator superfamily (mfs).
DR   OrthoDB; 626204at2; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR004748; Polyol_permease.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00897; 2A0118; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Sugar transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..425
FT                   /note="D-arabinitol transporter"
FT                   /id="PRO_0000050497"
FT   TOPO_DOM        1..7
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        8..28
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..51
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        73..80
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        102..107
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..128
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        129..141
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        163..172
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        173..193
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        194..237
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        238..258
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        259..263
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        264..284
FT                   /note="Helical; Name=8"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        285..295
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        296..316
FT                   /note="Helical; Name=9"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        317..323
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        324..344
FT                   /note="Helical; Name=10"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        345..360
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        361..381
FT                   /note="Helical; Name=11"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        382..383
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        384..404
FT                   /note="Helical; Name=12"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        405..425
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   425 AA;  46827 MW;  5544C2BFAB4EC215 CRC64;
     MSINNKQWLG LPLNLLWGYI AIAVFMTGDG FELAFLSHYI KALGFSPAEA SFAFTLYGLA
     AALSAWISGV VAEIITPLKT MMIGFVLWCV FHVLFLVFGL GHANYALILL FYGIRGFAYP
     LFLYSFIVAI VHNVKSDNAS SAIGWFWAVY SIGIGVFGSY IPSFTIPHIG EMGTLWLALA
     FCLTGGVIAL VSLRHIQTPQ HMQNLTTREK FSELGRAATL LYTNRNILLS SMVRIINTLS
     LFGFAVIMPM MFVDELGFST SEWLQVWAVF FFTTIFSNVL WGILGEKLGW MKVVRWFGCI
     GMALSSLAFY YIPQHFGHSF AMALIPAIAL GIFVAAFVPL AAVFPALEPK HKGAAISVYN
     LSAGMSNFLA PAIAVVLLPF FSTIGVVIAY TALYVVAFFL CAFIRVEQPG FSHKEATARE
     QVEFS