DANCR_HUMAN
ID DANCR_HUMAN Reviewed; 163 AA.
AC P0C864; A0A024RD90;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 49.
DE RecName: Full=Putative uncharacterized protein DANCR;
DE AltName: Full=Anti-differentiation ncRNA protein;
DE AltName: Full=Differentiation antagonizing non-protein coding RNA;
DE AltName: Full=Small nucleolar RNA host gene protein 13;
GN Name=DANCR; Synonyms=ANCR, KIAA0114, SNHG13;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 66-163.
RC TISSUE=Hepatoma;
RX PubMed=11752456; DOI=10.1073/pnas.241522398;
RA Xu X.R., Huang J., Xu Z.G., Qian B.Z., Zhu Z.D., Yan Q., Cai T., Zhang X.,
RA Xiao H.S., Qu J., Liu F., Huang Q.H., Cheng Z.H., Li N.G., Du J.J., Hu W.,
RA Shen K.T., Lu G., Fu G., Zhong M., Xu S.H., Gu W.Y., Huang W., Zhao X.T.,
RA Hu G.X., Gu J.R., Chen Z., Han Z.G.;
RT "Insight into hepatocellular carcinogenesis at transcriptome level by
RT comparing gene expression profiles of hepatocellular carcinoma with those
RT of corresponding noncancerous liver.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:15089-15094(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 81-163.
RC TISSUE=Hippocampus;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 85-163.
RC TISSUE=Bone marrow;
RX PubMed=7788527; DOI=10.1093/dnares/2.1.37;
RA Nagase T., Miyajima N., Tanaka A., Sazuka T., Seki N., Sato S., Tabata S.,
RA Ishikawa K., Kawarabayasi Y., Kotani H., Nomura N.;
RT "Prediction of the coding sequences of unidentified human genes. III. The
RT coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of
RT cDNA clones from human cell line KG-1.";
RL DNA Res. 2:37-43(1995).
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=22302877; DOI=10.1101/gad.182121.111;
RA Kretz M., Webster D.E., Flockhart R.J., Lee C.S., Zehnder A.,
RA Lopez-Pajares V., Qu K., Zheng G.X., Chow J., Kim G.E., Rinn J.L.,
RA Chang H.Y., Siprashvili Z., Khavari P.A.;
RT "Suppression of progenitor differentiation requires the long noncoding RNA
RT ANCR.";
RL Genes Dev. 26:338-343(2012).
CC -!- TISSUE SPECIFICITY: Expressed in keratinocytes.
CC {ECO:0000269|PubMed:22302877}.
CC -!- CAUTION: Product of a dubious CDS prediction. May be a non-coding RNA
CC (PubMed:22302877). {ECO:0000305|PubMed:22302877}.
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DR EMBL; CH471057; EAX05436.1; -; Genomic_DNA.
DR EMBL; CH471057; EAX05437.1; -; Genomic_DNA.
DR EMBL; AV698133; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BC045566; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; D28589; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; P0C864; -.
DR BioMuta; HGNC:28964; -.
DR jPOST; P0C864; -.
DR PRIDE; P0C864; -.
DR ProteomicsDB; 52400; -.
DR GeneCards; DANCR; -.
DR HGNC; HGNC:28964; DANCR.
DR MIM; 614625; gene.
DR neXtProt; NX_P0C864; -.
DR ChiTaRS; DANCR; human.
DR Pharos; P0C864; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; P0C864; protein.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..163
FT /note="Putative uncharacterized protein DANCR"
FT /id="PRO_0000348926"
FT CONFLICT 66
FT /note="P -> L (in Ref. 2; AV698133)"
FT /evidence="ECO:0000305"
FT CONFLICT 82
FT /note="L -> V (in Ref. 3; BC045566)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 163 AA; 16785 MW; C72FC9E1AEE75554 CRC64;
MAGPVPPHPG LAVRAAALHP APLRIFPGLA ELPDLSRGSA ARPALAQSLP GIGCGPRDPP
ASLPAPRRLS GLCARRRSQA SLSAGVARAD APLCSGFRAG HACGTGTQPQ PTLSSRSSSL
TSAEVQLPQF LAQVDNYRHK PLKLECPVAG ISIDLSQLSL QLQ