ID   DAPAL_CHLAA             Reviewed;         299 AA.
AC   A9WE23;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Uncharacterized DapA-like lyase Caur_1967;
DE            EC=4.-.-.-;
GN   OrderedLocusNames=Caur_1967;
OS   Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl).
OC   Bacteria; Chloroflexi; Chloroflexia; Chloroflexales; Chloroflexineae;
OC   Chloroflexaceae; Chloroflexus.
OX   NCBI_TaxID=324602;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29366 / DSM 635 / J-10-fl;
RX   PubMed=21714912; DOI=10.1186/1471-2164-12-334;
RA   Tang K.H., Barry K., Chertkov O., Dalin E., Han C.S., Hauser L.J.,
RA   Honchak B.M., Karbach L.E., Land M.L., Lapidus A., Larimer F.W.,
RA   Mikhailova N., Pitluck S., Pierson B.K., Blankenship R.E.;
RT   "Complete genome sequence of the filamentous anoxygenic phototrophic
RT   bacterium Chloroflexus aurantiacus.";
RL   BMC Genomics 12:334-334(2011).
CC   -!- SUBUNIT: Homotetramer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DapA family. {ECO:0000305}.
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DR   EMBL; CP000909; ABY35182.1; -; Genomic_DNA.
DR   RefSeq; WP_012257836.1; NC_010175.1.
DR   RefSeq; YP_001635571.1; NC_010175.1.
DR   AlphaFoldDB; A9WE23; -.
DR   SMR; A9WE23; -.
DR   STRING; 324602.Caur_1967; -.
DR   EnsemblBacteria; ABY35182; ABY35182; Caur_1967.
DR   KEGG; cau:Caur_1967; -.
DR   PATRIC; fig|324602.8.peg.2236; -.
DR   eggNOG; COG0329; Bacteria.
DR   HOGENOM; CLU_049343_5_1_0; -.
DR   InParanoid; A9WE23; -.
DR   OMA; QAIKLSM; -.
DR   Proteomes; UP000002008; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008840; F:4-hydroxy-tetrahydrodipicolinate synthase activity; IBA:GO_Central.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   InterPro; IPR020624; Schiff_base-form_aldolases_CS.
DR   PANTHER; PTHR12128; PTHR12128; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   PRINTS; PR00146; DHPICSNTHASE.
DR   SMART; SM01130; DHDPS; 1.
DR   PROSITE; PS00665; DHDPS_1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Lyase; Reference proteome; Schiff base.
FT   CHAIN           1..299
FT                   /note="Uncharacterized DapA-like lyase Caur_1967"
FT                   /id="PRO_0000340941"
FT   ACT_SITE        47
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        109
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        138
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        168
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   299 AA;  31677 MW;  F28252254D20E9AC CRC64;
     MAEPRGIISA MLTPFTSDVG PVDYEWLPGY LRFLADGGLH GVLALGTTGE GPSMSVAERI
     RTLEIIMAHR GELSVIAGTG CAALTDTIAL SRAAIDLGVD AILVMPPFYI KQPDETGILA
     YFRALCDALP ADARVMLYHI PQVTGVPITR TIIDGLLASH GTQFYGLKDS SGDWEHSKML
     IDSYPQLRIF TGSDRLIARA LAGGAAGAIT ALSSAFPKLA RAVFDAFHQG GDVAAAQARL
     SAVRDLVNPI NTPPALKAAL TWTSDLPETA LRLPLLPLSN EEVAALRAAY ERIMAGTTP