ID   DAPAL_PYRAR             Reviewed;         301 AA.
AC   A4WJK5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Uncharacterized DapA-like lyase Pars_0992;
DE            EC=4.-.-.-;
GN   Name=dapAL; OrderedLocusNames=Pars_0992;
OS   Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Pyrobaculum.
OX   NCBI_TaxID=340102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700994 / DSM 13514 / JCM 11321 / PZ6;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Cozen A.E.,
RA   Fitz-Gibbon S.T., House C.H., Saltikov C., Lowe T.M., Richardson P.;
RT   "Complete sequence of Pyrobaculum arsenaticum DSM 13514.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DapA family. {ECO:0000305}.
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DR   EMBL; CP000660; ABP50572.1; -; Genomic_DNA.
DR   AlphaFoldDB; A4WJK5; -.
DR   SMR; A4WJK5; -.
DR   STRING; 340102.Pars_0992; -.
DR   PRIDE; A4WJK5; -.
DR   EnsemblBacteria; ABP50572; ABP50572; Pars_0992.
DR   KEGG; pas:Pars_0992; -.
DR   HOGENOM; CLU_049343_5_1_2; -.
DR   OMA; LPPMRYK; -.
DR   PhylomeDB; A4WJK5; -.
DR   Proteomes; UP000001567; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008675; F:2-dehydro-3-deoxy-phosphogluconate aldolase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128; PTHR12128; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   PRINTS; PR00146; DHPICSNTHASE.
DR   SMART; SM01130; DHDPS; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Lyase; Schiff base.
FT   CHAIN           1..301
FT                   /note="Uncharacterized DapA-like lyase Pars_0992"
FT                   /id="PRO_1000050252"
FT   ACT_SITE        44
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        107
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        133
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        162
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   301 AA;  33135 MW;  02E8D6C0DBF35C80 CRC64;
     MKLEGVIAAT VTPFTKDGVN YEGLRIILSR IVEAGYHGVF PTSSTGEVTK LTPEERVKVM
     EVAKEVAGGK ALVIAGTGTG DHLSTIDMVR RYKDVGVDVV LITPPYYIQY DWAAIYAFYK
     KVLDKTDVPV ILYTIPLATG YNIPVEVFEL VANEYSQVVG VKDSSGDFRY HLDLIYLLGR
     RLSVLQGLDM LFVPSLIMGA HGGILAGPNF LGKTTLEQYR LVKEGKTAEA VSLHNKLMPL
     WRFMGGCGLV GKLGGKWPTL YKLATQLVHG IDMGPPREPL PPVEDKDRKE LEKILKELGL
     I