ID   ACT2_OXYFA              Reviewed;         357 AA.
AC   P02583;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Actin, cytoplasmic;
DE   AltName: Full=Actin, micronuclear;
OS   Oxytricha fallax.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX   NCBI_TaxID=5944;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=6799836; DOI=10.1038/295430a0;
RA   Kaine B.P., Spear B.B.;
RT   "Nucleotide sequence of a macronuclear gene for actin in Oxytricha
RT   fallax.";
RL   Nature 295:430-432(1982).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- PTM: Met-1 may be removed after translation.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   PIR; A03009; ATOQ.
DR   AlphaFoldDB; P02583; -.
DR   SMR; P02583; -.
DR   PRIDE; P02583; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..357
FT                   /note="Actin, cytoplasmic"
FT                   /id="PRO_0000088975"
SQ   SEQUENCE   357 AA;  39890 MW;  F5FE86F8F9B285DC CRC64;
     MSDQQTCVID NGSGVVKAGF AGEDAPRAVF PSIVGRPKNV SALIGVDSAS EYLGDEAQQK
     RGVLKIWNHT FYVELRVQPD EHPILLTEAP LSPKTNREKM TQIMFETFNV PALYVAIQAV
     LSLYSRGRTT GIVCDAGDGV THTVPIYEGF SIPHAVSRIQ LAGRDLTTFL AKLLTERGYN
     FTSSAELEIV RDIKEKLCFV ALNYESALKQ SHDSSQFEKN YELPDGKVIT IGSERFRCPE
     YLFKPLEMNG RELDSIQDLT YKSIQECDVD VRRDLYQNII LSGGTTMYEG IGERLLKEIE
     NRAPKSINVK VIASPDRRFA VWRGGSTLTS LSTFASMWIT KEDYDENGAS IVHRKCI