ID   ACT2_OXYTR              Reviewed;         375 AA.
AC   P53469;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Actin, cytoplasmic;
DE   AltName: Full=Actin, micronuclear;
OS   Oxytricha trifallax (Sterkiella histriomuscorum).
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Sterkiella.
OX   NCBI_TaxID=94289;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=WR;
RX   PubMed=7732002; DOI=10.1073/pnas.92.9.3888;
RA   Dubois M., Prescott D.M.;
RT   "Scrambling of the actin I gene in two Oxytricha species.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:3888-3892(1995).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U19288; AAA85839.1; -; Genomic_DNA.
DR   AlphaFoldDB; P53469; -.
DR   SMR; P53469; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..375
FT                   /note="Actin, cytoplasmic"
FT                   /id="PRO_0000088979"
SQ   SEQUENCE   375 AA;  41967 MW;  6F74A9AB37A80742 CRC64;
     MSDQQTCVID NGSGVVKAGF AGEDAPRAVF PSIVGRPKNV SALIGVDSAS EYLGDEAQQK
     RGVLKIFYPI EHGIVKDWDD MEKIWNHTFY VELRVQPDEH PILLTEAPLN PKTNREKMTQ
     IMFETFNVPA LYVVIQAVLS LYSAGSTTGI VCDAGDGVTH TVPIYEGFSI PHAVSRIQLA
     GRDLTTFMAK LLTERGYNFT SSAELEIVRD IKEKLCFVAL EYESALKQSH DSSQFEKNYE
     LPDGKVITIG SERFRCPEYL FKPLEMNGRE LDSIQDLTYK SIQECDVDVR RDLYQNIIIS
     GGTTMNEGIG ERLLKEIENR APKSINVKVI ASADRIFAVW RGGSTRTSLS TFASMWITKE
     DYDENGASIV HRKCI