ID   ACT2_SACKO              Reviewed;         376 AA.
AC   O18500;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Actin-2;
DE   Flags: Precursor;
OS   Saccoglossus kowalevskii (Acorn worm).
OC   Eukaryota; Metazoa; Hemichordata; Enteropneusta; Harrimaniidae;
OC   Saccoglossus.
OX   NCBI_TaxID=10224;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=9419242; DOI=10.1007/pl00006269;
RA   Bovenschulte M., Weber K.;
RT   "Deuterostomic actin genes and the definition of the chordates: cDNA
RT   cloning and gene organization for cephalochordates and hemichordates.";
RL   J. Mol. Evol. 45:653-660(1997).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; Y13665; CAA74016.1; -; mRNA.
DR   RefSeq; NP_001158423.1; NM_001164951.1.
DR   AlphaFoldDB; O18500; -.
DR   SMR; O18500; -.
DR   PRIDE; O18500; -.
DR   GeneID; 100303601; -.
DR   KEGG; sko:100303601; -.
DR   CTD; 109789; -.
DR   OrthoDB; 649708at2759; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   PROPEP          1..2
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000000716"
FT   CHAIN           3..376
FT                   /note="Actin-2"
FT                   /id="PRO_0000000717"
FT   MOD_RES         3
FT                   /note="N-acetylaspartate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   376 AA;  41883 MW;  B709521681C9E46C CRC64;
     MCDEEVAALV VDNGSGMCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ
     SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM
     TQIMFETFNT PAMYVAIQAV LSLYASGRTT GIVMDTGDGV THTVPIYEGY ALPHAILRLD
     LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFEQEMAT AASSSSLEKS
     YELPDGQVIT IGNERFRCPE ALFQPAFLGM ESPGIHETTY NSIMKCDIDI RKDLYAFSVL
     SGGTSMYPGI ADRMQKEITS LAPSSMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
     QEYDESGPSI VHRKCF