ID   ACT2_SCHCO              Reviewed;         375 AA.
AC   Q9Y896;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Actin-2;
GN   Name=ACT2; Synonyms=AKT2;
OS   Schizophyllum commune (Split gill fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Schizophyllaceae; Schizophyllum.
OX   NCBI_TaxID=5334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 44201 / CBS 340.81 / UVM 4-40 / 4-40;
RX   PubMed=10863093; DOI=10.1016/s0378-1119(00)00195-5;
RA   Tarkka M.T., Vasara R., Gorfer M., Raudaskoski M.;
RT   "Molecular characterization of actin genes from homobasidiomycetes: two
RT   different actin genes from Schizophyllum commune and Suillus bovinus.";
RL   Gene 251:27-35(2000).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; AF156270; AAD38204.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9Y896; -.
DR   SMR; Q9Y896; -.
DR   PRIDE; Q9Y896; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..375
FT                   /note="Actin-2"
FT                   /id="PRO_0000089003"
SQ   SEQUENCE   375 AA;  41794 MW;  7F73DE0667EBB4EB CRC64;
     MDDEIQAVVI DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH HGVMVGLSNK DSYVGDEAQA
     KRGVLTLKYP IEHGTVTNWD DMEKIWHHTY YNELRVAPEE HPVLLTEAPL NPKTNREKMT
     QIMFETFNVP AFHVSIQAVL SLYASGRTTG IVLDSGDGVT HTVPIYEGFS LPHAIQRLDL
     AGRDLTERLV LHLTERGYTF TTSAEKEVVR DIKERLCYVA LDFDQELITA AQSSALEKNY
     ELPDGQIITI GNERFRAPEV FFQPSFAGME SGGIADLVYT SIQRCDLDIR RELYGNIVMS
     GGTTMFPGIS DRMQRELSNM APANMKVKIV APPERKYSVW IGGSILASLS TFQNMWCSKQ
     EYDESGPGIV HRKCL