ID   ACT2_SOLTU              Reviewed;         336 AA.
AC   P93586;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Actin-46;
DE   Flags: Fragment;
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8896372; DOI=10.1093/oxfordjournals.molbev.a025685;
RA   Moniz de Sa M., Drouin G.;
RT   "Phylogeny and substitution rates of angiosperm actin genes.";
RL   Mol. Biol. Evol. 13:1198-1212(1996).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells. Essential component of cell cytoskeleton; plays an
CC       important role in cytoplasmic streaming, cell shape determination, cell
CC       division, organelle movement and extension growth.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- MISCELLANEOUS: There are at least 13 actin genes in potato.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; U60487; AAB40100.1; -; Genomic_DNA.
DR   AlphaFoldDB; P93586; -.
DR   SMR; P93586; -.
DR   PRIDE; P93586; -.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; P93586; baseline.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           <1..>336
FT                   /note="Actin-46"
FT                   /id="PRO_0000089009"
FT   NON_TER         1
FT   NON_TER         336
SQ   SEQUENCE   336 AA;  37089 MW;  795472AE4E0AD8F9 CRC64;
     AGFAGDDAPR AVFPSIVGRP RHAGVMVGMG QKDAYVGDEA QSKRGILTLK YPIEHGIVNN
     WDDMEKIWHH TFYNELRVAP EERPVLLTEA PLNPKANREK MTQIMFETFN APAMYVAIQA
     VLSLYASGRT TGIVLDSGDG VSHTVPIYEG YALPHAILRL DLAGADLTEY MVKILTERGY
     SFTTTAEKEI VRDMKEKLAY LALDFEQELE TTTTGSAVEK NYELPDGQVI TIGAERFRCP
     EVLYQPSLIG MEAAGIHETT YNSIMKCDVD IRKDLYGNIV LSGGSTMFPG IADRMSKEIQ
     ALAPSSMKIK VVAPPERKYS VWIGGSILAS LSTFQQ