ACT2_STENO
ID ACT2_STENO Reviewed; 375 AA.
AC P55805;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Actin, cytoplasmic;
DE AltName: Full=Actin, micronuclear;
GN Name=MIC-ACT-1;
GN and
GN Name=MIC-ACT-2;
OS Sterkiella nova (Ciliate) (Oxytricha nova).
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Stylonychinae; Sterkiella.
OX NCBI_TaxID=200597;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2503830; DOI=10.1073/pnas.86.16.6264;
RA Greslin A.F., Prescott D.M., Oka Y., Loukin S.H., Chappell J.C.;
RT "Reordering of nine exons is necessary to form a functional actin gene in
RT Oxytricha nova.";
RL Proc. Natl. Acad. Sci. U.S.A. 86:6264-6268(1989).
CC -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC various types of cell motility and are ubiquitously expressed in all
CC eukaryotic cells.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR EMBL; M25531; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; M25530; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; P55805; -.
DR SMR; P55805; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR004001; Actin_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
DR PROSITE; PS00406; ACTINS_1; 1.
DR PROSITE; PS00432; ACTINS_2; 1.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT CHAIN 1..375
FT /note="Actin, cytoplasmic"
FT /id="PRO_0000088977"
SQ SEQUENCE 375 AA; 41967 MW; 0AA8DE2597DDC280 CRC64;
MADKQTVVVD NGSGVVKAGF SGEDAPRAVF PSIIGRPKNV SALIGVDSAS EYIGDEAQQK
RGVLKIFYPI EHGIIKDWED MEKIWNHTFY VELRVQPDEH PVLLTEAPLN PKTNREKMTQ
IMFETFNVPA LYVAIQAVLS LYSAGRTTGI VCDAGDGVTH TVPIYEGFSI PHAVSRIQLA
GRDLTTFMAK LLTEKGYVFT SSAEMEIVRD IKEKLCFVAL DYEAAMKQSY ESTTFEKNYE
LPDGRVITIG NARFRCPEYL FKPLEMNGKE LDSIQSLTYN SIQECDVDVR RDLYQNIILS
GGTTMYEGIG ERLLKEIEAR APKSINVKVI ASPDRRFAVW RGGSTLTSLS TFASMWITKE
DYDENGASIV HRKCL