ID   ACT2_TETPY              Reviewed;         376 AA.
AC   P10993;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 2.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Actin, cytoplasmic;
DE   AltName: Full=Actin, micronuclear;
OS   Tetrahymena pyriformis.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae;
OC   Tetrahymena.
OX   NCBI_TaxID=5908;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3612802; DOI=10.1016/0022-2836(87)90367-6;
RA   Hirono M., Endoh H., Okada N., Numata O., Watanabe Y.;
RT   "Tetrahymena actin. Cloning and sequencing of the Tetrahymena actin gene
RT   and identification of its gene product.";
RL   J. Mol. Biol. 194:181-192(1987).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; X05195; CAA28824.1; -; Genomic_DNA.
DR   PIR; S07284; S07284.
DR   AlphaFoldDB; P10993; -.
DR   SMR; P10993; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..376
FT                   /note="Actin, cytoplasmic"
FT                   /id="PRO_0000089034"
SQ   SEQUENCE   376 AA;  42037 MW;  2DFCD4954AFFB2F3 CRC64;
     MTDSDSPAIV IDNGSGMCKA GIAGDDAPRA AFPSIIGRPK MPGIMVGMDQ KECYVGEEAQ
     AKRGVLNLKY PIEHGIVTDY DDMEKIWHHC FYNELRVTPE EHPCLLTEAP QNPKLNREKM
     TKTMFETFNV PSFYVAIQAV LSLYASGRTT GIVVDSGDGV THTVSIYEGY ALPHAILRID
     LAGRDLTEYC MKLLYEIGLN FSSTAEREII RDIKEKLCYV ALDYESELKA YKESSTNDKS
     YELPDGNTIT VQDQRFRCPE LLFKPAFIGK EFPGIHELTF NSIMKCDVDV RKDLYNNIVL
     SGGTTMFPGI AERLSKEVSA LAPSSMKIKV VAPPERRYSV WIGGSILSSL STFQTMWITK
     AEYDESGPSI VHRKCF