ID   ACT2_TRYBB              Reviewed;         376 AA.
AC   P12433;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Actin B;
OS   Trypanosoma brucei brucei.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=5702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3386635; DOI=10.1128/mcb.8.5.2166-2176.1988;
RA   Ben-Amar M.F., Pays A., Tebabi P., Dero B., Seebeck T., Steinert M.,
RA   Pays E.;
RT   "Structure and transcription of the actin gene of Trypanosoma brucei.";
RL   Mol. Cell. Biol. 8:2166-2176(1988).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; M20310; AAA30152.1; -; Genomic_DNA.
DR   AlphaFoldDB; P12433; -.
DR   SMR; P12433; -.
DR   GO; GO:0097014; C:ciliary plasm; IDA:GeneDB.
DR   GO; GO:0005737; C:cytoplasm; IDA:GeneDB.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..376
FT                   /note="Actin B"
FT                   /id="PRO_0000089047"
SQ   SEQUENCE   376 AA;  41882 MW;  846F71A207CE43DE CRC64;
     MSDEEQTAIV CDNGSGMVKS GFSGDDAPRH LFPSIVGPPK NEQAMMGSAK QEMFVGDEAQ
     AKRGVLALKY PIEHGIVTNW DDMEKVWHHT FYNELRVNPE SHNVLLTEAP MNPKQNREKM
     TQIMFETFGV PAMYVGIQAV LSLYSSGRTT GIVLDAGDGV THTVPIYEGY SLPHAIRRVD
     MAGRDLTEYL MKILMETGMT FTTSAQKEIV RNIKEQLCYV ALDFDEEMTN SAKSVSEEPF
     ELPDGNVMQV GNQRFRCPQA LFKPALIGLD EAPGFHEMTF QSINKCDIDV RRDLYGNIVL
     SGGTTMFKNL PERLGKEISN LAPSSIKPKV VAPPERKYSV WIGGSILSSL TTFQSMWITK
     SEYDESGPSI VHSKCF