ID   ACT3_CAEEL              Reviewed;         376 AA.
AC   P0DM42; P10983; P10985;
DT   26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2013, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Actin-3;
DE   Flags: Precursor;
GN   Name=act-3; ORFNames=T04C12.4;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2795655; DOI=10.1016/0022-2836(89)90503-2;
RA   Krause M., Wild M., Rosenzweig B., Hirsh D.;
RT   "Wild-type and mutant actin genes in Caenorhabditis elegans.";
RL   J. Mol. Biol. 208:381-392(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-86.
RX   PubMed=6302275; DOI=10.1016/0022-2836(83)90056-6;
RA   Files J.G., Carr S., Hirsh D.;
RT   "Actin gene family of Caenorhabditis elegans.";
RL   J. Mol. Biol. 164:355-375(1983).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- MISCELLANEOUS: In this organism there are four genes coding for actin.
CC       The sequences coded by genes 1 and 3 are identical. There are a few
CC       variations in the actins coded by genes 2 and 4.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; X16798; CAA34719.1; -; Genomic_DNA.
DR   EMBL; Z81584; CAB04676.1; -; Genomic_DNA.
DR   EMBL; J01044; AAA27889.1; -; Genomic_DNA.
DR   PIR; S16710; S16710.
DR   RefSeq; NP_505817.1; NM_073416.6.
DR   RefSeq; NP_505819.1; NM_073418.5.
DR   AlphaFoldDB; P0DM42; -.
DR   SMR; P0DM42; -.
DR   BioGRID; 44560; 2.
DR   BioGRID; 44562; 11.
DR   EPD; P0DM42; -.
DR   EnsemblMetazoa; T04C12.4.1; T04C12.4.1; WBGene00000065.
DR   EnsemblMetazoa; T04C12.4.2; T04C12.4.2; WBGene00000065.
DR   EnsemblMetazoa; T04C12.4.3; T04C12.4.3; WBGene00000065.
DR   GeneID; 179535; -.
DR   KEGG; cel:CELE_T04C12.6; -.
DR   CTD; 179535; -.
DR   WormBase; T04C12.4; CE13148; WBGene00000065; act-3.
DR   GeneTree; ENSGT00950000182960; -.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   OrthoDB; 649708at2759; -.
DR   PhylomeDB; P0DM42; -.
DR   SignaLink; P0DM42; -.
DR   PRO; PR:P0DM42; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00000065; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0005865; C:striated muscle thin filament; IDA:WormBase.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IGI:WormBase.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IGI:WormBase.
DR   GO; GO:0000281; P:mitotic cytokinesis; IGI:WormBase.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   Acetylation; ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW   Reference proteome.
FT   PROPEP          1..2
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000422648"
FT   CHAIN           3..376
FT                   /note="Actin-3"
FT                   /id="PRO_0000422649"
FT   MOD_RES         3
FT                   /note="N-acetylaspartate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   376 AA;  41796 MW;  BCF86DE909D4EE0D CRC64;
     MCDDEVAALV VDNGSGMCKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ
     SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM
     TQIMFETFNT PAMYVAIQAV LSLYASGRTT GVVLDSGDGV THTVPIYEGY ALPHAILRLD
     LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFEQEMAT AASSSSLEKS
     YELPDGQVIT VGNERFRCPE AMFQPSFLGM ESAGIHETSY NSIMKCDIDI RKDLYANTVL
     SGGTTMYPGI ADRMQKEITA LAPSTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
     QEYDESGPSI VHRKCF