ID   3608L_ASFB7             Reviewed;         319 AA.
AC   P23162;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   23-FEB-2022, entry version 63.
DE   RecName: Full=Protein MGF 360-8L;
GN   OrderedLocusNames=BA71V-023; ORFNames=J319L;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2325203; DOI=10.1128/jvi.64.5.2073-2081.1990;
RA   Gonzalez A., Calvo V., Almazan F., Almendral J.M., Ramirez J.C.,
RA   de la Vega I., Blasco R., Vinuela E.;
RT   "Multigene families in African swine fever virus: family 360.";
RL   J. Virol. 64:2073-2081(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [3]
RP   FUNCTION.
RX   PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA   Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA   Rock D.L.;
RT   "African swine fever virus multigene family 360 and 530 genes are novel
RT   macrophage host range determinants.";
RL   J. Virol. 75:3066-3076(2001).
RN   [4]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages.
CC       {ECO:0000269|PubMed:11238833}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 360 family. {ECO:0000305}.
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DR   EMBL; M57543; AAA42676.1; -; Genomic_DNA.
DR   EMBL; U18466; AAA65254.1; -; Genomic_DNA.
DR   PIR; D43680; D43680.
DR   RefSeq; NP_042718.1; NC_001659.2.
DR   SMR; P23162; -.
DR   GeneID; 22220388; -.
DR   KEGG; vg:22220388; -.
DR   Proteomes; UP000000624; Genome.
DR   GO; GO:0042330; P:taxis; IEA:InterPro.
DR   InterPro; IPR002595; ASFV_MGF360.
DR   Pfam; PF01671; ASFV_360; 1.
PE   2: Evidence at transcript level;
KW   Early protein; Reference proteome.
FT   CHAIN           1..319
FT                   /note="Protein MGF 360-8L"
FT                   /id="PRO_0000221947"
SQ   SEQUENCE   319 AA;  37719 MW;  AF2A8F6BAA8F22C7 CRC64;
     MLSLQTLAKK AVAKQSVPEE YHYILKYCGL WWQNKPISLC HYCNYVILSS TPFKGELLHL
     DVALIMAIKE NNYDVIRLFT EWGANIYYGL TCARTEQTQE LCRKLGAKDG LNNKEIFAGL
     MRHKTSNNII LCHEIFDKNP MLEALNVQEM GEEIHRELKL FIFYILDNVP MNIFVKYWYA
     IAVKYKLKRA IFFFYQTYGH LSMWRLMCAI YFNNVFDLHE IYEQKIVHMD IDKMMQLACM
     QDYNFLTIYY CFVLGADIDQ AITVTQWHYH TNNLYFCKDL KDLKQNTLTA RPLLLPNITD
     PKKIYTMLKN YLPTSSNSL