ID   ACT4_TOBAC              Reviewed;         336 AA.
AC   P93372;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Actin-66;
DE   Flags: Fragment;
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8896372; DOI=10.1093/oxfordjournals.molbev.a025685;
RA   Moniz de Sa M., Drouin G.;
RT   "Phylogeny and substitution rates of angiosperm actin genes.";
RL   Mol. Biol. Evol. 13:1198-1212(1996).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells. Essential component of cell cytoskeleton; plays an
CC       important role in cytoplasmic streaming, cell shape determination, cell
CC       division, organelle movement and extension growth.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- MISCELLANEOUS: There are at least 7 different actin genes in tobacco.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; U60491; AAB40087.1; -; Genomic_DNA.
DR   AlphaFoldDB; P93372; -.
DR   SMR; P93372; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           <1..>336
FT                   /note="Actin-66"
FT                   /id="PRO_0000089040"
FT   NON_TER         1
FT   NON_TER         336
SQ   SEQUENCE   336 AA;  37187 MW;  6717F2B3AC9EC0C5 CRC64;
     AGFAGDDAPR AVFPSIVGRP RHTGVMVGMG QKDAYIGDEA QSKRGILTLK YPIEHGIVSN
     WDDMEKIWHH TFYNELRVAP EEHPWLLTEA PLNPKANREK MTQIMFETFN VPAMYVAIQA
     VLSLYASGRT TGIVLDSGDG VSHTVPIYEG YALPHAILRL DLAGRDLTDC LMKILTERGY
     SFTTSAEREI VRDVKEKLAY VALDYEQELE TAKSSSSVEK SYELPDGQVI TIGSERFRCP
     EVLFQPSLVG MEAAGIHETT YNSIMKCDVD IRKDLYGNIV LSGGTTMFPG IADRMSKEIT
     ALAPSSMKIK VVAPPERKYS VWIGGSILAS LSTFQQ