ID   ACT5_ARATH              Reviewed;         378 AA.
AC   Q8RYC2; P93737;
DT   25-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 127.
DE   RecName: Full=Putative actin-5;
GN   Name=ACT5; OrderedLocusNames=At2g42100; ORFNames=T24P15.22, T6D20.1;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY ORGANIZATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=8852856; DOI=10.1093/genetics/142.2.587;
RA   McDowell J.M., Huang S., McKinney E.C., An Y.-Q., Meagher R.B.;
RT   "Structure and evolution of the actin gene family in Arabidopsis
RT   thaliana.";
RL   Genetics 142:587-602(1996).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells. Essential component of cell cytoskeleton; plays an
CC       important role in cytoplasmic streaming, cell shape determination, cell
CC       division, organelle movement and extension growth.
CC   -!- SUBUNIT: Polymerization of globular actin (G-actin) leads to a
CC       structural filament (F-actin) in the form of a two-stranded helix. The
CC       binding of profilin to monomeric G-actin cause the sequestration of
CC       actin into profilactin complexes, and prevents the polymerization.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- MISCELLANEOUS: There are 8 actin genes in A.thaliana.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF18605.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AC002561; AAF18605.2; ALT_INIT; Genomic_DNA.
DR   EMBL; U90439; AAM15522.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC10070.1; -; Genomic_DNA.
DR   PIR; H84849; H84849.
DR   PIR; T00920; T00920.
DR   RefSeq; NP_181740.1; NM_129773.1.
DR   AlphaFoldDB; Q8RYC2; -.
DR   SMR; Q8RYC2; -.
DR   BioGRID; 4147; 2.
DR   STRING; 3702.AT2G42100.1; -.
DR   PaxDb; Q8RYC2; -.
DR   PRIDE; Q8RYC2; -.
DR   EnsemblPlants; AT2G42100.1; AT2G42100.1; AT2G42100.
DR   GeneID; 818810; -.
DR   Gramene; AT2G42100.1; AT2G42100.1; AT2G42100.
DR   KEGG; ath:AT2G42100; -.
DR   Araport; AT2G42100; -.
DR   TAIR; locus:2059959; AT2G42100.
DR   eggNOG; KOG0676; Eukaryota.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   InParanoid; Q8RYC2; -.
DR   OMA; CYIAVDY; -.
DR   OrthoDB; 649708at2759; -.
DR   PhylomeDB; Q8RYC2; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q8RYC2; baseline and differential.
DR   Genevisible; Q8RYC2; AT.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005829; C:cytosol; HDA:TAIR.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   5: Uncertain;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..378
FT                   /note="Putative actin-5"
FT                   /id="PRO_0000088891"
SQ   SEQUENCE   378 AA;  42117 MW;  802AF8372A687138 CRC64;
     MSDLGDESVA IVCDNGTGMV KAGFAGDDAP RAVFPSVVGR PRHRGVMVGM DEKDTFVGDE
     AQARRGILSL KYPIEHGVVS NWDDMEKIWH HTFYNELRLE PEEHPILLTE APLNPKVNRE
     KMTQIMFESF AFPSMYIGIQ AVLSLYSSGR TTGIVLDSGD GVSHTVPIYE GYALPHAILR
     LDLAGRDLTE YLTKIMMERG YTYTTSAERE IVRDIKEKLC YIAVDYEQEM EKATTSSAID
     RTYELPDGQV ITIGAERFRC PEVLFQTSLI GMETSGIHET TYNSIMKCDV DIRKDLYGNI
     VLSGGTTMFP GIADRMNKEI NALAPPSMKI KVVAPPERKY SVWVGGSILA SLSSFAPMWI
     TKAEYDEQGG AIVHRKCF