ID   ACTC_STYPL              Reviewed;         375 AA.
AC   Q00215;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Actin, cytoplasmic;
OS   Styela plicata (Wrinkled sea squirt) (Ascidia plicata).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Stolidobranchia;
OC   Styelidae; Styela.
OX   NCBI_TaxID=7726;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=8315656; DOI=10.1007/bf00182183;
RA   Kovilur S., Jacobson J.W., Beach R.L., Jeffery W.R., Tomlinson C.R.;
RT   "Evolution of the chordate muscle actin gene.";
RL   J. Mol. Evol. 36:361-368(1993).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBUNIT: Polymerization of globular actin (G-actin) leads to a
CC       structural filament (F-actin) in the form of a two-stranded helix. Each
CC       actin can bind to 4 others.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   PIR; S33386; S33386.
DR   AlphaFoldDB; Q00215; -.
DR   SMR; Q00215; -.
DR   PRIDE; Q00215; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..375
FT                   /note="Actin, cytoplasmic"
FT                   /id="PRO_0000089030"
SQ   SEQUENCE   375 AA;  41930 MW;  2D5A065BE93D9E0D CRC64;
     MDDEVAALVV DNGSGMCKAG FAEDDAPRAV FPSIVGRPRH QGVMVGMVQK DSYVGDEAQS
     KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT
     QIMFETFNTR AMYVNIQAVL SLYASGRTTG LVMDSGDGVS HTVPIYEGYA LPHAIFRLDL
     AGRDLTDYLM KILTERGYSF TTTAEREIVR DIKEKLCYVG LDFESEMGTA SSSSVLEKSY
     ELPDGQVITI GNERFRCPEA MFQPSFLGME SAGIHETTYN SIMKCDVDIR KDLYANTVLS
     GGTTMYPGIA DRMQKEISAL APPTMKIKII APPERKYSVW IGGSILASLS TFQQMWISKQ
     EYDESGPSIV HRKCF