ID   ACTE_STRPU              Reviewed;         376 AA.
AC   P53474;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Actin, cytoskeletal 3A;
DE   AltName: Full=Actin, cytoskeletal IIIA;
DE   Flags: Precursor;
GN   Name=CYIIIA;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3612803; DOI=10.1016/0022-2836(87)90368-8;
RA   Akhurst R.J., Calzone F.J., Lee J.J., Britten R.J., Davidson E.H.;
RT   "Structure and organization of the CyIII actin gene subfamily of the sea
RT   urchin, Strongylocentrotus purpuratus.";
RL   J. Mol. Biol. 194:193-203(1987).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; M30511; AAA30030.1; -; Genomic_DNA.
DR   EMBL; M29808; AAA30030.1; JOINED; Genomic_DNA.
DR   RefSeq; NP_999694.1; NM_214529.1.
DR   AlphaFoldDB; P53474; -.
DR   SMR; P53474; -.
DR   GeneID; 373298; -.
DR   KEGG; spu:373298; -.
DR   CTD; 373298; -.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   InParanoid; P53474; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   Acetylation; ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW   Reference proteome.
FT   PROPEP          1..2
FT                   /note="Removed in mature form"
FT                   /id="PRO_0000000730"
FT   CHAIN           3..376
FT                   /note="Actin, cytoskeletal 3A"
FT                   /id="PRO_0000000731"
FT   MOD_RES         3
FT                   /note="N-acetylaspartate"
FT                   /evidence="ECO:0000250"
FT   UNSURE          112
FT   UNSURE          122
FT   UNSURE          144
FT   UNSURE          277
FT   UNSURE          286
SQ   SEQUENCE   376 AA;  41904 MW;  A522FFC3EEB4CD8D CRC64;
     MCDDDVAALV VDNGSGMVKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ
     SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM
     TQIMFETFNS PAMYVAIQAV LSLYASGRTT GIVFDSGDGV SHTVPIYEGY ALPHAIIRLD
     LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFEQEMQT AASSSSLEKS
     YELPDGQVIT IGNERFRASE TLFQPSFIGM ESAGIHETCY NRIMKCDVDI RKDLYVNTVL
     SGGSTMFPGI ADRMQKEISA LAPPTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
     QEYDESGPSI VHRKCF