ID   ACTF_STRPU              Reviewed;         376 AA.
AC   P18499;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Actin, cytoskeletal 3B;
DE   AltName: Full=Actin, cytoskeletal IIIB;
DE   Flags: Precursor;
GN   Name=CYIIIB;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3148745; DOI=10.1007/bf02143499;
RA   Durica D.S., Garza D., Restrepo M.A., Hryniewicz M.M.;
RT   "DNA sequence analysis and structural relationships among the cytoskeletal
RT   actin genes of the sea urchin Strongylocentrotus purpuratus.";
RL   J. Mol. Evol. 28:72-86(1988).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton.
CC   -!- TISSUE SPECIFICITY: Confined to aboral ectoderm cells.
CC   -!- DEVELOPMENTAL STAGE: Sea urchin larval development.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; M35324; AAA30043.1; -; Genomic_DNA.
DR   RefSeq; NP_999692.1; NM_214527.1.
DR   AlphaFoldDB; P18499; -.
DR   SMR; P18499; -.
DR   STRING; 7668.SPU_009433-tr; -.
DR   PRIDE; P18499; -.
DR   EnsemblMetazoa; NM_214527; NP_999692; GeneID_373296.
DR   GeneID; 373296; -.
DR   KEGG; spu:373296; -.
DR   CTD; 373296; -.
DR   eggNOG; KOG0676; Eukaryota.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   InParanoid; P18499; -.
DR   OrthoDB; 649708at2759; -.
DR   PhylomeDB; P18499; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW   Reference proteome.
FT   PROPEP          1..2
FT                   /note="Removed in mature form"
FT                   /id="PRO_0000000732"
FT   CHAIN           3..376
FT                   /note="Actin, cytoskeletal 3B"
FT                   /id="PRO_0000000733"
FT   MOD_RES         3
FT                   /note="N-acetylaspartate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   376 AA;  41832 MW;  EEA27C722553EE5F CRC64;
     MCDDDVAALV VDNGSGMVKA GFAGDDAPRA VFPSIVGRPR HQGVMVGMGQ KDSYVGDEAQ
     SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM
     TQIMFETFNS PAMYVAIQAV LSLYASGRTT GIVFDSGDGV SHTVPIYEGY ALPHAIIRLD
     LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYV ALDFEEEMQT AASSSSLEKS
     YELPDGQVIT IGNERFRCSE TLLQPSFIGM ESAGIHETCY NSIMKCDVDI RKDLYANTVL
     SGASTMFPGI ADRMQKEIVA LAPPTMKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
     QEYDESGPSI VHRKCF