ACTG_EMENI
ID ACTG_EMENI Reviewed; 375 AA.
AC P20359; C8V0S4; Q5AYT8;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 26-MAY-2009, sequence version 2.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Actin, gamma;
GN Name=acnA; ORFNames=AN6542;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2975248; DOI=10.1016/0378-1119(88)90200-4;
RA Fidel S., Doonan J.H., Morris N.R.;
RT "Aspergillus nidulans contains a single actin gene which has unique intron
RT locations and encodes a gamma-actin.";
RL Gene 70:283-293(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC various types of cell motility and are ubiquitously expressed in all
CC eukaryotic cells.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR EMBL; M22869; AAA33290.1; -; Genomic_DNA.
DR EMBL; AACD01000109; EAA57882.1; -; Genomic_DNA.
DR EMBL; BN001301; CBF70950.1; -; Genomic_DNA.
DR PIR; JT0385; JT0385.
DR RefSeq; XP_664146.1; XM_659054.1.
DR AlphaFoldDB; P20359; -.
DR SMR; P20359; -.
DR STRING; 162425.CADANIAP00007315; -.
DR PRIDE; P20359; -.
DR EnsemblFungi; CBF70950; CBF70950; ANIA_06542.
DR EnsemblFungi; EAA57882; EAA57882; AN6542.2.
DR GeneID; 2870269; -.
DR KEGG; ani:AN6542.2; -.
DR VEuPathDB; FungiDB:AN6542; -.
DR eggNOG; KOG0676; Eukaryota.
DR HOGENOM; CLU_027965_0_2_1; -.
DR InParanoid; P20359; -.
DR OMA; FHTTAER; -.
DR OrthoDB; 649708at2759; -.
DR Proteomes; UP000000560; Chromosome I.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0001411; C:hyphal tip; IMP:AspGD.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR004001; Actin_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
DR PROSITE; PS00406; ACTINS_1; 1.
DR PROSITE; PS00432; ACTINS_2; 1.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 3: Inferred from homology;
KW ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW Reference proteome.
FT CHAIN 1..375
FT /note="Actin, gamma"
FT /id="PRO_0000088936"
FT CONFLICT 129
FT /note="A -> V (in Ref. 1; AAA33290)"
FT /evidence="ECO:0000305"
FT CONFLICT 259
FT /note="E -> K (in Ref. 1; AAA33290)"
FT /evidence="ECO:0000305"
FT CONFLICT 283
FT /note="M -> I (in Ref. 1; AAA33290)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 375 AA; 41639 MW; 0520E7883A359B80 CRC64;
MEEEVAALVI DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH HGIMIGMGQK DSYVGDEAQS
KRGILTLRYP IEHGVVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPI NPKSNREKMT
QIVFETFNAP AFYVSIQAVL SLYASGRTTG IVLDSGDGVT HVVPIYEGFA LPHAISRVDM
AGRDLTDYLM KILAERGYTF STTAEREIVR DIKEKLCYVA LDFEQEIQTA SQSSSLEKSY
ELPDGQVITI GNERFRAPEA LFQPSVLGLE SGGIHVTTFN SIMKCDVDVR KDLYGNIVMS
GGTTMYPGIS DRMQKEITAL APSSMKVKII APPERKYSVW IGGSILASLS TFQQMWISKQ
EYDESGPSIV HRKCF
