ID   ACTL9_BOVIN             Reviewed;         416 AA.
AC   Q2T9W4;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Actin-like protein 9;
GN   Name=ACTL9; Synonyms=ACTL7C;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Testis-specic protein that plays an important role in fusion
CC       of proacrosomal vesicles and perinuclear theca formation.
CC       {ECO:0000250|UniProtKB:Q8TC94}.
CC   -!- SUBUNIT: Interacts with ACTL7A. {ECO:0000250|UniProtKB:Q8TC94}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, acrosome
CC       {ECO:0000250|UniProtKB:Q8TC94}. Cytoplasm, cytoskeleton, perinuclear
CC       theca {ECO:0000250|UniProtKB:Q8TC94}. Note=Localizes predominantly in
CC       the equatorial segment of the sperm head and neck regions, with some
CC       localization in the acrosomal segment of the head. Colocalizes in the
CC       acrosomal and equatorial segments of sperm with ACTL7A. Colocalizes
CC       with PLCZ1 in the equatorial segment of the head of capacitated sperm.
CC       {ECO:0000250|UniProtKB:Q8TC94}.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; BC111236; AAI11237.1; -; mRNA.
DR   RefSeq; NP_001033658.1; NM_001038569.2.
DR   AlphaFoldDB; Q2T9W4; -.
DR   SMR; Q2T9W4; -.
DR   STRING; 9913.ENSBTAP00000014947; -.
DR   PaxDb; Q2T9W4; -.
DR   Ensembl; ENSBTAT00000014947; ENSBTAP00000014947; ENSBTAG00000011255.
DR   GeneID; 540051; -.
DR   KEGG; bta:540051; -.
DR   CTD; 284382; -.
DR   VEuPathDB; HostDB:ENSBTAG00000011255; -.
DR   VGNC; VGNC:25580; ACTL9.
DR   eggNOG; KOG0676; Eukaryota.
DR   GeneTree; ENSGT00940000163012; -.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   InParanoid; Q2T9W4; -.
DR   OMA; MYVAYQS; -.
DR   OrthoDB; 649708at2759; -.
DR   TreeFam; TF354237; -.
DR   Proteomes; UP000009136; Chromosome 7.
DR   Bgee; ENSBTAG00000011255; Expressed in spermatid and 9 other tissues.
DR   GO; GO:0001669; C:acrosomal vesicle; ISS:UniProtKB.
DR   GO; GO:0005869; C:dynactin complex; IBA:GO_Central.
DR   GO; GO:0033011; C:perinuclear theca; ISS:UniProtKB.
DR   GO; GO:0061827; C:sperm head; ISS:UniProtKB.
DR   GO; GO:0001675; P:acrosome assembly; ISS:UniProtKB.
DR   GO; GO:0009566; P:fertilization; ISS:UniProtKB.
DR   GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR030074; ACTL9.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   PANTHER; PTHR11937:SF194; PTHR11937:SF194; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Fertilization;
KW   Reference proteome.
FT   CHAIN           1..416
FT                   /note="Actin-like protein 9"
FT                   /id="PRO_0000332296"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   416 AA;  45566 MW;  F23C9BD108EE5F74 CRC64;
     MDPNQGNPLE PQDSPEIPKP SLNLSSILAK STLPQEPPSM VGDRLPPKTG AVVIDMGTGT
     CKVGFAGQAR PTYTVATIVG CQPQKPATSG QPVMETFIGE AARKRPELTL VQPVHSGIVV
     DWDAAELIWR HMLEHDLRVA TRDHPLLFSD PPFSPSTNRE KLVEVAFESL SSPAMYVASQ
     SVLSVYAHGR VSGLVVDTGH GVTYTVPVFQ GYNLPHATQR LDLAGTHLTA FLAEMLLGSG
     LPLGQQDLDT VENIKHRYCY VAPDFLKEQA RPELECRQTL KLPDGRTVTL GKELFQCPEL
     LFSPPEIPGL SPVGVPTMAQ QSLSKVAAEL RTDLAQNVLL CGGSSLFTGF QARFQTELLR
     NLPPEAHVVV MAQPTRNFSV WIGGSILASL RTFQSCWVLR EQYEEQGPYI VYRKCY