ID   DAPF_ORYSI              Reviewed;         357 AA.
AC   A2ZLS4;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Putative diaminopimelate epimerase, chloroplastic;
DE            Short=DAP epimerase;
DE            EC=5.1.1.7;
DE   Flags: Precursor;
GN   Name=DAPF; ORFNames=OsI_037517;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-
CC         diaminoheptanedioate; Xref=Rhea:RHEA:15393, ChEBI:CHEBI:57609,
CC         ChEBI:CHEBI:57791; EC=5.1.1.7;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC       pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the diaminopimelate epimerase family.
CC       {ECO:0000305}.
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DR   EMBL; CM000137; EAY83558.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2ZLS4; -.
DR   SMR; A2ZLS4; -.
DR   STRING; 39946.A2ZLS4; -.
DR   EnsemblPlants; BGIOSGA037614-TA; BGIOSGA037614-PA; BGIOSGA037614.
DR   Gramene; BGIOSGA037614-TA; BGIOSGA037614-PA; BGIOSGA037614.
DR   HOGENOM; CLU_053306_2_1_1; -.
DR   OMA; HVAMRVH; -.
DR   UniPathway; UPA00034; UER00025.
DR   Proteomes; UP000007015; Chromosome 12.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0008837; F:diaminopimelate epimerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009089; P:lysine biosynthetic process via diaminopimelate; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_00197; DAP_epimerase; 1.
DR   InterPro; IPR018510; DAP_epimerase_AS.
DR   InterPro; IPR001653; DAP_epimerase_DapF.
DR   PANTHER; PTHR31689; PTHR31689; 1.
DR   Pfam; PF01678; DAP_epimerase; 2.
DR   TIGRFAMs; TIGR00652; DapF; 1.
DR   PROSITE; PS01326; DAP_EPIMERASE; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Chloroplast; Isomerase; Lysine biosynthesis;
KW   Plastid; Reference proteome; Transit peptide.
FT   TRANSIT         1..47
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           48..357
FT                   /note="Putative diaminopimelate epimerase, chloroplastic"
FT                   /id="PRO_0000307180"
FT   ACT_SITE        145
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        300
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   357 AA;  38075 MW;  4454E4D184C04096 CRC64;
     MSSATAAATA TIAAAAAAAA KLAATPAPAP SRRRLTLRGN PTARRCVAAM AVSTPRSAAA
     AAFLERRESE RALHFVKYQG LGNDFIMMDN RDSAVPKVTP EEAAKLCDRN FGVGADGVIF
     VMPGVNGADY TMRIFNSDGS EPEMCGNGVR CFARFIAELE NLQGTHSFKI HTGAGLIIPE
     IQNDGKVKVD MGQPILSGPD IPTKLPSTKN EAVVQADLAV DGSTWQVTCV SMGNPHCVTF
     GTKELKVLHV DDLKLSDIGP KFEHHEMFPA RTNTEFVEVL SRSHLKMRVW ERGAGATLAC
     GTGACAVVVA AVLEGRAERK CVVDLPGGPL EIEWREDDNH IYMTGPAEAV FYGSAVH