ID   ACTM_STRPU              Reviewed;         374 AA.
AC   P12431;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Actin, muscle;
DE   Flags: Precursor;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3114500; DOI=10.1007/bf02100039;
RA   Crain W.R. Jr., Boshar M.F., Cooper A.D., Durica D.S., Nagy A., Steffen D.;
RT   "The sequence of a sea urchin muscle actin gene suggests a gene conversion
RT   with a cytoskeletal actin gene.";
RL   J. Mol. Evol. 25:37-45(1987).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-15.
RX   PubMed=2831500; DOI=10.1093/nar/16.4.1431;
RA   Nisson P.E., Hickey R.J., Boshar M.F., Crain W.R. Jr.;
RT   "Identification of a repeated sequence in the genome of the sea urchin
RT   which is transcribed by RNA polymerase III and contains the features of a
RT   retroposon.";
RL   Nucleic Acids Res. 16:1431-1452(1988).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; X05739; CAA29199.1; -; Genomic_DNA.
DR   EMBL; X05740; CAA29199.1; JOINED; Genomic_DNA.
DR   EMBL; X05741; CAA29199.1; JOINED; Genomic_DNA.
DR   EMBL; X05742; CAA29199.1; JOINED; Genomic_DNA.
DR   EMBL; X05743; CAA29199.1; JOINED; Genomic_DNA.
DR   EMBL; X07085; CAA30118.1; -; Genomic_DNA.
DR   PIR; A29664; A29664.
DR   PIR; S00706; S00706.
DR   RefSeq; NP_001119777.1; NM_001126305.1.
DR   PRIDE; P12431; -.
DR   GeneID; 581500; -.
DR   KEGG; spu:581500; -.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   OrthoDB; 649708at2759; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   Acetylation; ATP-binding; Cytoplasm; Cytoskeleton; Muscle protein;
KW   Nucleotide-binding; Reference proteome.
FT   PROPEP          1..2
FT                   /note="Removed in mature form"
FT                   /id="PRO_0000000734"
FT   CHAIN           3..374
FT                   /note="Actin, muscle"
FT                   /id="PRO_0000000735"
FT   MOD_RES         3
FT                   /note="N-acetylaspartate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   374 AA;  41557 MW;  DE444683EBA46BD1 CRC64;
     MCDEDVAALV VDNGSGMCKT GFAGDDAPRA VFPSIVGRPR HHGVMVGMGQ KDSYVGDEAQ
     SKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANREKM
     TQIMFETFNA PAMYVAIKAV LSLYASGRTT GIXXXXGDGV THTVPIYEGY ALPHAILRLD
     LAGRDLTDYL MKILTERGYS FTTTAEREIV RDIKEKLCYT ALNFEREMAT AAASSSLEKS
     YELPDGQVIT IGNERFRCPE TLFEPAFIGM ESAGIHETTY NSIMKCDIDI RKDLYANTVL
     SGGTSMYPGI ADRMQKEITA LAPSSVKIKI IAPPERKYSV WIGGSILASL STFQQMWISK
     QEYSGASIVH RKCF