ACTN_STYCL
ID ACTN_STYCL Reviewed; 378 AA.
AC P53475;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Actin, muscle;
GN Name=TB12;
GN and
GN Name=TB34;
OS Styela clava (Sea squirt).
OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Stolidobranchia;
OC Styelidae; Styela.
OX NCBI_TaxID=7725;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1577198; DOI=10.1016/0012-1606(92)90213-z;
RA Beach R.L., Jeffery W.R.;
RT "Multiple actin genes encoding the same alpha-muscle isoform are expressed
RT during ascidian development.";
RL Dev. Biol. 151:55-66(1992).
CC -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC various types of cell motility and are ubiquitously expressed in all
CC eukaryotic cells.
CC -!- SUBUNIT: Polymerization of globular actin (G-actin) leads to a
CC structural filament (F-actin) in the form of a two-stranded helix. Each
CC actin can bind to 4 others.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR EMBL; L13790; AAA29848.1; -; mRNA.
DR EMBL; L13787; AAA29845.1; -; mRNA.
DR PIR; A43911; A43911.
DR AlphaFoldDB; P53475; -.
DR SMR; P53475; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR InterPro; IPR004000; Actin.
DR InterPro; IPR020902; Actin/actin-like_CS.
DR InterPro; IPR004001; Actin_CS.
DR InterPro; IPR043129; ATPase_NBD.
DR PANTHER; PTHR11937; PTHR11937; 1.
DR Pfam; PF00022; Actin; 1.
DR PRINTS; PR00190; ACTIN.
DR SMART; SM00268; ACTIN; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
DR PROSITE; PS00406; ACTINS_1; 1.
DR PROSITE; PS00432; ACTINS_2; 1.
DR PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE 2: Evidence at transcript level;
KW ATP-binding; Cytoplasm; Cytoskeleton; Muscle protein; Nucleotide-binding.
FT CHAIN 1..378
FT /note="Actin, muscle"
FT /id="PRO_0000089028"
SQ SEQUENCE 378 AA; 42043 MW; 6EB4BDDBAFBD305E CRC64;
MSDGEEDQTA IVCDNGSGLV KSGFAGDDAP RAVFPSIVGR PRHQGVMVGM GQKDSYVGDE
AQSKRGILTL KYPIEHGIIT NWDDMEKIWH HTMYNELRVA PEEHPTLLTE APLNPKANRE
KMTQIMFETF NVPAMYVAIQ AVLSLYASGR TTGIVMDAGD GVSHNVPIYE GYALPHAIAR
LDLAGRDLTD YLMKILTERG YSFVTTAERE IVRDIKEKLC YVALDFEQEM ATAASSTSLE
KSYELPDGQV ITIGNERFRC PETLFQPSFI GMESAGIHET TYNSIMKCDI DIRKDLYANN
VLSGGTTMYP GIADRMQKEI TALAPSTMKI KIIAPPERKY SVWIGGSILA SLSTFQQMWI
SKQEYDEAGP SIVHRKCF