ID   ACTOB_DICDI             Reviewed;          90 AA.
AC   Q55DU1;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Actobindin-B/C;
GN   Name=abnB; ORFNames=DDB_G0269518;
GN   and
GN   Name=abnC; ORFNames=DDB_G0269520;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Is able to bind two actin monomers at high concentrations of
CC       G-actin. Inhibits actin polymerization by sequestering G-actin and
CC       stabilizing actin dimers (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAFI02000005; EAL72109.1; -; Genomic_DNA.
DR   EMBL; AAFI02000005; EAL72110.1; -; Genomic_DNA.
DR   RefSeq; XP_646039.1; XM_640947.1.
DR   RefSeq; XP_646040.1; XM_640948.1.
DR   AlphaFoldDB; Q55DU1; -.
DR   SMR; Q55DU1; -.
DR   PaxDb; Q55DU1; -.
DR   EnsemblProtists; EAL72109; EAL72109; DDB_G0269518.
DR   EnsemblProtists; EAL72110; EAL72110; DDB_G0269520.
DR   GeneID; 8616986; -.
DR   GeneID; 8616987; -.
DR   KEGG; ddi:DDB_G0269518; -.
DR   KEGG; ddi:DDB_G0269520; -.
DR   dictyBase; DDB_G0269518; abnB.
DR   dictyBase; DDB_G0269520; abnC.
DR   eggNOG; ENOG502SBN0; Eukaryota.
DR   HOGENOM; CLU_175897_0_0_1; -.
DR   InParanoid; Q55DU1; -.
DR   OMA; HVETQDR; -.
DR   PRO; PR:Q55DU1; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0005829; C:cytosol; IDA:dictyBase.
DR   GO; GO:0031012; C:extracellular matrix; HDA:dictyBase.
DR   GO; GO:0003779; F:actin binding; ISS:dictyBase.
DR   InterPro; IPR016365; Actobindin.
DR   InterPro; IPR003124; WH2_dom.
DR   Pfam; PF02205; WH2; 2.
DR   PIRSF; PIRSF002724; Actobindin; 1.
DR   SMART; SM00246; WH2; 2.
DR   PROSITE; PS51082; WH2; 2.
PE   3: Inferred from homology;
KW   Actin-binding; Reference proteome; Repeat.
FT   CHAIN           1..90
FT                   /note="Actobindin-B/C"
FT                   /id="PRO_0000383095"
FT   DOMAIN          4..21
FT                   /note="WH2 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00406"
FT   DOMAIN          40..57
FT                   /note="WH2 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00406"
FT   REGION          57..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   90 AA;  9640 MW;  3C54B8C20A34C24E CRC64;
     MSTTANPLLA EINKGTDLKH AETQDKSAPI IENVPIKKND HSSLLGEVEK GAQLKHVETQ
     DRSAPVTEGA TVKSNNHSAL LGEIKSKAQE