ID   DAW1_BOVIN              Reviewed;         415 AA.
AC   Q0P593;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Dynein assembly factor with WDR repeat domains 1;
DE   AltName: Full=Outer row dynein assembly protein 16 homolog;
DE   AltName: Full=WD repeat-containing protein 69;
GN   Name=DAW1; Synonyms=WDR69;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hippocampus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in axonemal outer row dynein assembly.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR69 family. {ECO:0000305}.
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DR   EMBL; BC120334; AAI20335.1; -; mRNA.
DR   RefSeq; NP_001069398.1; NM_001075930.1.
DR   AlphaFoldDB; Q0P593; -.
DR   SMR; Q0P593; -.
DR   STRING; 9913.ENSBTAP00000028431; -.
DR   PaxDb; Q0P593; -.
DR   PRIDE; Q0P593; -.
DR   Ensembl; ENSBTAT00000028431; ENSBTAP00000028431; ENSBTAG00000021327.
DR   GeneID; 530118; -.
DR   KEGG; bta:530118; -.
DR   CTD; 164781; -.
DR   VEuPathDB; HostDB:ENSBTAG00000021327; -.
DR   VGNC; VGNC:27883; DAW1.
DR   eggNOG; KOG0272; Eukaryota.
DR   GeneTree; ENSGT00940000167309; -.
DR   InParanoid; Q0P593; -.
DR   OMA; TGQCSQV; -.
DR   OrthoDB; 872177at2759; -.
DR   Proteomes; UP000009136; Chromosome 2.
DR   Bgee; ENSBTAG00000021327; Expressed in oviduct epithelium and 44 other tissues.
DR   GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0019005; C:SCF ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:1990756; F:ubiquitin ligase-substrate adaptor activity; IBA:GO_Central.
DR   GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 4.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 8.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 8.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 4.
DR   PROSITE; PS50082; WD_REPEATS_2; 8.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..415
FT                   /note="Dynein assembly factor with WDR repeat domains 1"
FT                   /id="PRO_0000293711"
FT   REPEAT          90..129
FT                   /note="WD 1"
FT   REPEAT          132..174
FT                   /note="WD 2"
FT   REPEAT          175..214
FT                   /note="WD 3"
FT   REPEAT          217..256
FT                   /note="WD 4"
FT   REPEAT          259..298
FT                   /note="WD 5"
FT   REPEAT          301..340
FT                   /note="WD 6"
FT   REPEAT          343..384
FT                   /note="WD 7"
FT   REPEAT          386..415
FT                   /note="WD 8"
SQ   SEQUENCE   415 AA;  45857 MW;  2BD372D048A11223 CRC64;
     MKLKSLLLRY YPPGIMLEYE KSGQLKTKSI DLLDLDPSTD VSALVEEIQK AEPLITASRS
     DQVKLLIQRL QNKLGQHSNH KFYLFKVLRA HILPLTNVAL NKSGSCFITG SYDRTCKLWD
     TASGEELHTL EGHRNVVYAI AFNNPYGDKI ATGSFDKTCK LWSVETGKCY HTFRGHTAEI
     VCLSFNPQST LVATGSMDTT AKLWDIQSGE EVFTLTGHSA EIISLSFNTS GNRIITGSFD
     HTVTVWEADT GRKVYTLIGH CAEISSAVFN WDCSLILTGS MDKTCKLWDA VNGKCVATLT
     GHDDEILDSC FDYTGKLIAT ASADGTARIF SAATRECVTK LEGHEGEISK ISFNPQGNRL
     LTGSSDKTAR IWDAQTGQCL QVLEGHTDEI FSCAFNYKGD IIITGSKDNT CRIWR