ID   DAW1_MACFA              Reviewed;         415 AA.
AC   Q4R8E7;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Dynein assembly factor with WDR repeat domains 1;
DE   AltName: Full=Outer row dynein assembly protein 16 homolog;
DE   AltName: Full=WD repeat-containing protein 69;
GN   Name=DAW1; Synonyms=WDR69; ORFNames=QtsA-12631;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in axonemal outer row dynein assembly.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR69 family. {ECO:0000305}.
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DR   EMBL; AB168505; BAE00625.1; -; mRNA.
DR   RefSeq; NP_001270824.1; NM_001283895.1.
DR   AlphaFoldDB; Q4R8E7; -.
DR   SMR; Q4R8E7; -.
DR   STRING; 9541.XP_005574565.1; -.
DR   GeneID; 101865836; -.
DR   CTD; 164781; -.
DR   eggNOG; KOG0272; Eukaryota.
DR   OrthoDB; 872177at2759; -.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 4.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 8.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 8.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 4.
DR   PROSITE; PS50082; WD_REPEATS_2; 8.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..415
FT                   /note="Dynein assembly factor with WDR repeat domains 1"
FT                   /id="PRO_0000242655"
FT   REPEAT          90..129
FT                   /note="WD 1"
FT   REPEAT          132..174
FT                   /note="WD 2"
FT   REPEAT          175..214
FT                   /note="WD 3"
FT   REPEAT          217..256
FT                   /note="WD 4"
FT   REPEAT          259..298
FT                   /note="WD 5"
FT   REPEAT          301..340
FT                   /note="WD 6"
FT   REPEAT          343..384
FT                   /note="WD 7"
FT   REPEAT          386..415
FT                   /note="WD 8"
SQ   SEQUENCE   415 AA;  45740 MW;  87AB45AD3268A040 CRC64;
     MKLKSFLLRY YPPGIMLEYE KHGELKTKSI DLLDLGPSTD VSALVEEIQK AEPLITASRT
     EQVKLLIQRL QEKLGQHSNH TFYLFKVLKA HILPLTNVAL NKSGSCFITG SYDRTCKLWD
     TASGEELNTL EGHRNVVYAI AFNNPYGDKT ATGSFDKTCK LWSVETGKCY HTFRGHTAEI
     VCLSFNPQST LVATGSMDTT AKLWNIQNGE EVCTLRGHSA EIISLSFNTS GDRIITGSFD
     HTVVVWDADT GGKVNILIGH CAEISSALFN WDCSLILTGS MDKTCMLWDA TNGKCVATLT
     GHDDEILDSC FDYTGKLIAT ASADGTARIF SAATRKCIAK LEGHEGEISK ISFNPQGNRL
     LTGSSDKTAR IWDAQTGQCL QVLEGHTDEI FSCTFNYKGN IVITGSKDNT CRIWR