ID   DAW1_XENLA              Reviewed;         415 AA.
AC   Q5FWQ6;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Dynein assembly factor with WDR repeat domains 1;
DE   AltName: Full=Outer row dynein assembly protein 16 homolog;
DE   AltName: Full=WD repeat-containing protein 69;
GN   Name=daw1; Synonyms=wdr69;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in axonemal outer row dynein assembly.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR69 family. {ECO:0000305}.
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DR   EMBL; BC089247; AAH89247.1; -; mRNA.
DR   RefSeq; NP_001089233.1; NM_001095764.1.
DR   AlphaFoldDB; Q5FWQ6; -.
DR   SMR; Q5FWQ6; -.
DR   DNASU; 734280; -.
DR   GeneID; 734280; -.
DR   KEGG; xla:734280; -.
DR   CTD; 734280; -.
DR   Xenbase; XB-GENE-5802553; daw1.S.
DR   OrthoDB; 872177at2759; -.
DR   Proteomes; UP000186698; Chromosome 5S.
DR   Bgee; 734280; Expressed in testis and 19 other tissues.
DR   GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 4.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 8.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 8.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 3.
DR   PROSITE; PS50082; WD_REPEATS_2; 8.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..415
FT                   /note="Dynein assembly factor with WDR repeat domains 1"
FT                   /id="PRO_0000242658"
FT   REPEAT          90..129
FT                   /note="WD 1"
FT   REPEAT          132..174
FT                   /note="WD 2"
FT   REPEAT          175..214
FT                   /note="WD 3"
FT   REPEAT          217..256
FT                   /note="WD 4"
FT   REPEAT          259..298
FT                   /note="WD 5"
FT   REPEAT          301..340
FT                   /note="WD 6"
FT   REPEAT          343..384
FT                   /note="WD 7"
FT   REPEAT          386..415
FT                   /note="WD 8"
SQ   SEQUENCE   415 AA;  45918 MW;  50F4A6387A255FDE CRC64;
     MRLKRFLLRY FPPGIILEYE KGGELKTKAI DLLELSPTTD VDLVVGEIQK AEPLITASRT
     QQVKQLILRL QEKIGQQDSR QFYLFKVLRA HILPLTNVAF NKSGSSFITG SYDRTCKVWD
     TASGEELHTL EGHRNVVYAI QFNNPYGDKI ATGSFDKTCK LWSAETGKCY HTFRGHTAEI
     VCLVFNPQST LIATGSMDTT AKLWDIQSGE EALTLSGHAA EIISLSFNTT GDRLITGSFD
     HTVSVWEIPS GRRIHTLIGH RGEISSAQFN WDCSLIATAS MDKSCKLWDS LNGKCVATLT
     GHDDEVLDVT FDSTGQLVAT ASADGTARVY SASSRKCLAK LEGHEGEISK ICFNAQGNRI
     VTASSDKTSR LWDPHTGECL QVLKGHTDEI FSCAFNYEGN TIITGSKDNT CRIWR