ID   DAW1_XENTR              Reviewed;         415 AA.
AC   Q6P2Y2;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Dynein assembly factor with WDR repeat domains 1;
DE   AltName: Full=Outer row dynein assembly protein 16 homolog;
DE   AltName: Full=WD repeat-containing protein 69;
GN   Name=daw1; Synonyms=wdr69;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in axonemal outer row dynein assembly.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the WD repeat WDR69 family. {ECO:0000305}.
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DR   EMBL; BC064252; AAH64252.1; -; mRNA.
DR   RefSeq; NP_989349.1; NM_204018.1.
DR   AlphaFoldDB; Q6P2Y2; -.
DR   SMR; Q6P2Y2; -.
DR   PaxDb; Q6P2Y2; -.
DR   DNASU; 394975; -.
DR   GeneID; 394975; -.
DR   KEGG; xtr:394975; -.
DR   CTD; 164781; -.
DR   Xenbase; XB-GENE-5802528; daw1.
DR   eggNOG; KOG0272; Eukaryota.
DR   InParanoid; Q6P2Y2; -.
DR   OrthoDB; 872177at2759; -.
DR   Proteomes; UP000008143; Chromosome 5.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0019005; C:SCF ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:1990756; F:ubiquitin ligase-substrate adaptor activity; IBA:GO_Central.
DR   GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 4.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 8.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 8.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 3.
DR   PROSITE; PS50082; WD_REPEATS_2; 8.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..415
FT                   /note="Dynein assembly factor with WDR repeat domains 1"
FT                   /id="PRO_0000242659"
FT   REPEAT          90..129
FT                   /note="WD 1"
FT   REPEAT          132..174
FT                   /note="WD 2"
FT   REPEAT          175..214
FT                   /note="WD 3"
FT   REPEAT          217..256
FT                   /note="WD 4"
FT   REPEAT          259..298
FT                   /note="WD 5"
FT   REPEAT          301..340
FT                   /note="WD 6"
FT   REPEAT          343..384
FT                   /note="WD 7"
FT   REPEAT          386..415
FT                   /note="WD 8"
SQ   SEQUENCE   415 AA;  45989 MW;  307F68FFAD70FC84 CRC64;
     MRLKRFLLRY FPPGIILEYE KGGELKTKAI DLLELSPTTD VDLVVEEIQK AEPLITASRT
     QQVKQLILRL QEKIGQQDSR QFYLFKVLRA HILPLTNVAF NKSGSSFITG SYDRTCKVWD
     TASGEELHTL EGHRNVVYAI QFNNPYGDKI ATGSFDKTCK LWSAETGKCY HTFRGHTAEI
     VCLAFNPQST LIATGSMDTT AKLWDIQSGE EALTLSGHAA EIISLSFNTT GDRLITGSFD
     HTVSVWEIPS GRRIHTLIGH RGEISSAQFN WDCSLIATAS MDKSCKLWDS LNGKCVATLT
     GHEDEVLDVT FDSTGQLVAT ASADGTARVY SASSRKCLAK LEGHEGEISK ICFNAQGNRI
     LTASSDKTSR LWNPHTGECL QVLKGHTDEI FSCAFNYEGN TIITGSKDNT CRIWR