ID   38K_NPVAC               Reviewed;         320 AA.
AC   P24745;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 2.
DT   29-SEP-2021, entry version 62.
DE   RecName: Full=Uncharacterized 38.0 kDa protein in P143-LEF5 intergenic region;
DE   AltName: Full=ORF2;
OS   Autographa californica nuclear polyhedrosis virus (AcMNPV).
OC   Viruses; Naldaviricetes; Lefavirales; Baculoviridae; Alphabaculovirus.
OX   NCBI_TaxID=46015;
OH   NCBI_TaxID=7088; Lepidoptera (butterflies and moths).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C6;
RX   PubMed=8030224; DOI=10.1006/viro.1994.1380;
RA   Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.;
RT   "The complete DNA sequence of Autographa californica nuclear polyhedrosis
RT   virus.";
RL   Virology 202:586-605(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HR3;
RX   PubMed=1994581; DOI=10.1016/0042-6822(91)90500-b;
RA   Lu A., Carstens E.B.;
RT   "Nucleotide sequence of a gene essential for viral DNA replication in the
RT   baculovirus Autographa californica nuclear polyhedrosis virus.";
RL   Virology 181:336-347(1991).
RN   [3]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=16987976; DOI=10.1128/jvi.01155-06;
RA   Wu W., Lin T., Pan L., Yu M., Li Z., Pang Y., Yang K.;
RT   "Autographa californica multiple nucleopolyhedrovirus nucleocapsid assembly
RT   is interrupted upon deletion of the 38K gene.";
RL   J. Virol. 80:11475-11485(2006).
RN   [4]
RP   FUNCTION, SUBCELLULAR LOCATION, AND INTERACTION WITH PROTEINS VP1054; VP39
RP   AND VP80.
RX   PubMed=18922869; DOI=10.1128/jvi.00948-08;
RA   Wu W., Liang H., Kan J., Liu C., Yuan M., Liang C., Yang K., Pang Y.;
RT   "Autographa californica multiple nucleopolyhedrovirus 38K is a novel
RT   nucleocapsid protein that interacts with VP1054, VP39, VP80, and itself.";
RL   J. Virol. 82:12356-12364(2008).
CC   -!- FUNCTION: Plays a role in nucleocapsid assembly and is essential for
CC       viral replication. Distributed over the cylindrical capsid sheath of
CC       nucleocapsid. {ECO:0000269|PubMed:16987976,
CC       ECO:0000269|PubMed:18922869}.
CC   -!- SUBUNIT: Interacts with VP1054, VP39 and VP80.
CC       {ECO:0000269|PubMed:18922869}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:18922869}. Host
CC       nucleus {ECO:0000269|PubMed:16987976}. Host cytoplasm
CC       {ECO:0000269|PubMed:16987976}.
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DR   EMBL; L22858; AAA66728.1; -; Genomic_DNA.
DR   EMBL; M57687; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; C72862; C72862.
DR   RefSeq; NP_054128.1; NC_001623.1.
DR   PRIDE; P24745; -.
DR   GeneID; 1403931; -.
DR   KEGG; vg:1403931; -.
DR   Proteomes; UP000008292; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.1000; -; 1.
DR   InterPro; IPR007827; DUF705.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR010033; HAD_SF_ppase_IIIC.
DR   Pfam; PF05152; DUF705; 1.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   TIGRFAMs; TIGR01681; HAD-SF-IIIC; 1.
DR   TIGRFAMs; TIGR01684; viral_ppase; 1.
PE   1: Evidence at protein level;
KW   Host cytoplasm; Host nucleus; Reference proteome; Virion.
FT   CHAIN           1..320
FT                   /note="Uncharacterized 38.0 kDa protein in P143-LEF5
FT                   intergenic region"
FT                   /id="PRO_0000133031"
SQ   SEQUENCE   320 AA;  38022 MW;  CCA5864B4AB40CDB CRC64;
     MASSLQSKWI CLRLNDAIIK RHVLVLSEYA DLKYLGFEKY KFFEYVIFQF CNDPQLCKII
     ENNYNYCMQI FKAPADDMRD IRHNIKRAFK TPVLGHMCVL SNKPPMYSFL KEWFLLPHYK
     VVSLKSESLT WGFPHVVVFD LDSTLITEEE QVEIRDPFVY DSLQELHEMG CVLVLWSYGS
     RDHVAHSMRD VDLEGYFDII ISEGSTVQEE RSDLVQNSHN AIVDYNLKKR FIENKFVFDI
     HNHRSDNNIP KSPKIVIKYL SDKNVNFFKS ITLVDDLPTN NYAYDFYVKV KRCPTPVQDW
     EHYHNEIIQN IMDYEQYFIK