ID   DAZP2_BOVIN             Reviewed;         168 AA.
AC   Q3T0K9;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=DAZ-associated protein 2;
DE   AltName: Full=Deleted in azoospermia-associated protein 2;
GN   Name=DAZAP2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts with DAZ1 and DAZL. Interacts with SOX6. Interacts
CC       with IL17RB. May interact with FAM168B. Interacts with INCA1.
CC       {ECO:0000250|UniProtKB:Q15038, ECO:0000250|UniProtKB:Q9DCP9}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC       Note=Predominantly nuclear in macrophages, stimulation of IL17RB with
CC       its ligand IL17E induces accumulation in the cytoplasm. {ECO:0000250}.
CC   -!- PTM: Ubiquitinated by SMURF2, leading to proteasomal degradation.
CC       {ECO:0000250}.
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DR   EMBL; BC102352; AAI02353.1; -; mRNA.
DR   RefSeq; NP_001029873.1; NM_001034701.1.
DR   AlphaFoldDB; Q3T0K9; -.
DR   STRING; 9913.ENSBTAP00000002573; -.
DR   PaxDb; Q3T0K9; -.
DR   PRIDE; Q3T0K9; -.
DR   Ensembl; ENSBTAT00000002573; ENSBTAP00000002573; ENSBTAG00000004349.
DR   GeneID; 540286; -.
DR   KEGG; bta:540286; -.
DR   CTD; 9802; -.
DR   VEuPathDB; HostDB:ENSBTAG00000004349; -.
DR   VGNC; VGNC:27886; DAZAP2.
DR   eggNOG; ENOG502QTNQ; Eukaryota.
DR   GeneTree; ENSGT00390000000685; -.
DR   HOGENOM; CLU_135110_0_0_1; -.
DR   InParanoid; Q3T0K9; -.
DR   OMA; IYQPRYM; -.
DR   OrthoDB; 1175298at2759; -.
DR   TreeFam; TF329672; -.
DR   Proteomes; UP000009136; Chromosome 5.
DR   Bgee; ENSBTAG00000004349; Expressed in leukocyte and 106 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016607; C:nuclear speck; IEA:Ensembl.
DR   GO; GO:0032991; C:protein-containing complex; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IEA:Ensembl.
DR   GO; GO:0043539; F:protein serine/threonine kinase activator activity; IEA:Ensembl.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IEA:Ensembl.
DR   GO; GO:0050699; F:WW domain binding; IEA:Ensembl.
DR   InterPro; IPR022730; DAZ_assoc-2.
DR   PANTHER; PTHR31638; PTHR31638; 1.
DR   Pfam; PF11029; DAZAP2; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome; Ubl conjugation.
FT   CHAIN           1..168
FT                   /note="DAZ-associated protein 2"
FT                   /id="PRO_0000285817"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   168 AA;  17319 MW;  49F1B6D281E24AAC CRC64;
     MNSKGQYPTQ PTYPVQPPGN PVYPQTLHLP QAPPYTDAPP AYSELYRPSF VHPGAATVPT
     MSAAFPGASL YLPMAQSVAV GPLGSTIPMA YYPVGPIYPP GSTVLVEGGY DAGARFGAGA
     TAGNIPPPPP GCPPNAAQLA VMQGANVLVT QRKGNFFMGG SDGGYTIW