ID   DB128_MACFA             Reviewed;          93 AA.
AC   A4H255;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Beta-defensin 128;
DE   AltName: Full=Defensin, beta 128;
DE   Flags: Precursor;
GN   Name=DEFB128;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Hollox E.J., Armour J.A.L.;
RT   "Evolution and sequence variation of human beta-defensin genes.";
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Has antibacterial activity. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the beta-defensin family. {ECO:0000305}.
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DR   EMBL; AM410160; CAL68970.1; -; Genomic_DNA.
DR   RefSeq; XP_005568665.1; XM_005568608.2.
DR   AlphaFoldDB; A4H255; -.
DR   SMR; A4H255; -.
DR   STRING; 9541.XP_005568665.1; -.
DR   GeneID; 102132494; -.
DR   KEGG; mcf:102132494; -.
DR   CTD; 245939; -.
DR   VEuPathDB; HostDB:ENSMFAG00000003500; -.
DR   eggNOG; ENOG502TM18; Eukaryota.
DR   OMA; ISEMGCL; -.
DR   OrthoDB; 1568261at2759; -.
DR   Proteomes; UP000233100; Chromosome 10.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:InterPro.
DR   InterPro; IPR025933; Beta_defensin.
DR   Pfam; PF13841; Defensin_beta_2; 1.
PE   3: Inferred from homology;
KW   Antibiotic; Antimicrobial; Defensin; Disulfide bond; Reference proteome;
KW   Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..93
FT                   /note="Beta-defensin 128"
FT                   /id="PRO_0000289852"
FT   DISULFID        24..52
FT                   /evidence="ECO:0000250"
FT   DISULFID        32..46
FT                   /evidence="ECO:0000250"
FT   DISULFID        36..53
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   93 AA;  10634 MW;  8A86371E8531CF1E CRC64;
     MKLFLVLIIL LFEVLTDGAR LKKCFNNVTG YCRKKCKVGE IHEIGCLSGK LCCVNDEENK
     KHVPFKKPHQ QPVEKLSVQQ DYVILPTITI FTV