ID   DB132_MACFA             Reviewed;          95 AA.
AC   A4H265;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Beta-defensin 132;
DE   AltName: Full=Defensin, beta 132;
DE   Flags: Precursor;
GN   Name=DEFB132;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Hollox E.J., Armour J.A.L.;
RT   "Evolution and sequence variation of human beta-defensin genes.";
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Has antibacterial activity. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the beta-defensin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM410170; CAL68986.1; -; Genomic_DNA.
DR   RefSeq; XP_005568663.1; XM_005568606.2.
DR   AlphaFoldDB; A4H265; -.
DR   STRING; 9541.XP_005568663.1; -.
DR   Ensembl; ENSMFAT00000074602; ENSMFAP00000052372; ENSMFAG00000064390.
DR   GeneID; 102131746; -.
DR   KEGG; mcf:102131746; -.
DR   CTD; 400830; -.
DR   VEuPathDB; HostDB:ENSMFAG00000033994; -.
DR   eggNOG; ENOG502TE15; Eukaryota.
DR   GeneTree; ENSGT00940000165094; -.
DR   OMA; NASRKCC; -.
DR   OrthoDB; 1570128at2759; -.
DR   Proteomes; UP000233100; Chromosome 10.
DR   GO; GO:0005615; C:extracellular space; IEA:Ensembl.
DR   GO; GO:0061827; C:sperm head; IEA:Ensembl.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:InterPro.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:Ensembl.
DR   InterPro; IPR025933; Beta_defensin.
DR   Pfam; PF13841; Defensin_beta_2; 1.
PE   3: Inferred from homology;
KW   Antibiotic; Antimicrobial; Defensin; Disulfide bond; Reference proteome;
KW   Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..95
FT                   /note="Beta-defensin 132"
FT                   /id="PRO_0000289860"
FT   REGION          72..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        27..55
FT                   /evidence="ECO:0000250"
FT   DISULFID        35..49
FT                   /evidence="ECO:0000250"
FT   DISULFID        39..56
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   95 AA;  10569 MW;  3B812E11B0F55171 CRC64;
     MKFLLLVLAA LGFLTQVIPA SGGGSKCVSD TPGYCRTHCH RGETALFMCS PFRKCCISYS
     FLPQPDLPQL IGNHWPSRSR NTQRKNKKQQ TTVTP