ID   DBH1_STRLI              Reviewed;          93 AA.
AC   P0A3H6; O06447;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=DNA-binding protein HU 1;
DE   AltName: Full=HSl;
GN   Name=hup1; Synonyms=hup;
OS   Streptomyces lividans.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1916;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=TK24;
RX   PubMed=9294002; DOI=10.1016/s0167-4781(97)00089-4;
RA   Yokoyama E., Doi K., Ogata S.;
RT   "Cloning and sequencing of the hup gene encoding the histone-like protein
RT   HSl of Streptomyces lividans.";
RL   Biochim. Biophys. Acta 1353:103-106(1997).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; AB001381; BAA19970.1; -; Genomic_DNA.
DR   EMBL; AB033486; BAA85334.1; -; Genomic_DNA.
DR   AlphaFoldDB; P0A3H6; -.
DR   SMR; P0A3H6; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding.
FT   CHAIN           1..93
FT                   /note="DNA-binding protein HU 1"
FT                   /id="PRO_0000104976"
SQ   SEQUENCE   93 AA;  9851 MW;  E9653EA7FE8C02CE CRC64;
     MNRSELVAAL ADRAEVTRKD ADAVLAAFAE VVGDIVSKGD EKVTIPGFLT FERTHRAART
     ARNPQTGEPI QIPAGYSVKV SAGSKLKEAA KGK