ID   DBHA_BURPS              Reviewed;          92 AA.
AC   P0DMK4; Q63Z33; Q9ZF89;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   09-JUL-2014, sequence version 1.
DT   03-AUG-2022, entry version 31.
DE   RecName: Full=DNA-binding protein HU-alpha;
GN   Name=hupA; OrderedLocusNames=BPSL0004;
OS   Burkholderia pseudomallei (strain K96243).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=272560;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K96243;
RX   PubMed=15377794; DOI=10.1073/pnas.0403302101;
RA   Holden M.T.G., Titball R.W., Peacock S.J., Cerdeno-Tarraga A.-M.,
RA   Atkins T., Crossman L.C., Pitt T., Churcher C., Mungall K.L., Bentley S.D.,
RA   Sebaihia M., Thomson N.R., Bason N., Beacham I.R., Brooks K., Brown K.A.,
RA   Brown N.F., Challis G.L., Cherevach I., Chillingworth T., Cronin A.,
RA   Crossett B., Davis P., DeShazer D., Feltwell T., Fraser A., Hance Z.,
RA   Hauser H., Holroyd S., Jagels K., Keith K.E., Maddison M., Moule S.,
RA   Price C., Quail M.A., Rabbinowitsch E., Rutherford K., Sanders M.,
RA   Simmonds M., Songsivilai S., Stevens K., Tumapa S., Vesaratchavest M.,
RA   Whitehead S., Yeats C., Barrell B.G., Oyston P.C.F., Parkhill J.;
RT   "Genomic plasticity of the causative agent of melioidosis, Burkholderia
RT   pseudomallei.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14240-14245(2004).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions. {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; BX571965; CAH33987.1; -; Genomic_DNA.
DR   RefSeq; WP_004195781.1; NZ_CP009538.1.
DR   RefSeq; YP_106629.1; NC_006350.1.
DR   AlphaFoldDB; P0DMK4; -.
DR   SMR; P0DMK4; -.
DR   STRING; 272560.BPSL0004; -.
DR   EnsemblBacteria; CAH33987; CAH33987; BPSL0004.
DR   GeneID; 56593937; -.
DR   GeneID; 66545373; -.
DR   KEGG; bps:BPSL0004; -.
DR   PATRIC; fig|272560.51.peg.1746; -.
DR   eggNOG; COG0776; Bacteria.
DR   OMA; ISQEKQC; -.
DR   Proteomes; UP000000605; Chromosome 1.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding; Reference proteome.
FT   CHAIN           1..92
FT                   /note="DNA-binding protein HU-alpha"
FT                   /id="PRO_0000104927"
SQ   SEQUENCE   92 AA;  9621 MW;  FCFBD5A359EDDA0C CRC64;
     MNKQELIDAV AAQTGASKAQ TGETLDTLLE VIKKAVSKGD SVQLIGFGSF GSGKRAARTG
     RNPKTGETIK IPAAKTVKFT AGKAFKDAVN KR