ID   DBHA_PSEAE              Reviewed;          90 AA.
AC   Q9HTL0;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=DNA-binding protein HU-alpha;
GN   Name=hupA; OrderedLocusNames=PA5348;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions. {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; AE004091; AAG08733.1; -; Genomic_DNA.
DR   PIR; F82976; F82976.
DR   RefSeq; NP_254035.1; NC_002516.2.
DR   RefSeq; WP_003096630.1; NC_002516.2.
DR   AlphaFoldDB; Q9HTL0; -.
DR   SMR; Q9HTL0; -.
DR   STRING; 287.DR97_2719; -.
DR   PaxDb; Q9HTL0; -.
DR   PRIDE; Q9HTL0; -.
DR   DNASU; 879642; -.
DR   EnsemblBacteria; AAG08733; AAG08733; PA5348.
DR   GeneID; 879642; -.
DR   KEGG; pae:PA5348; -.
DR   PATRIC; fig|208964.12.peg.5604; -.
DR   PseudoCAP; PA5348; -.
DR   HOGENOM; CLU_105066_3_1_6; -.
DR   InParanoid; Q9HTL0; -.
DR   OMA; PAFKISK; -.
DR   PhylomeDB; Q9HTL0; -.
DR   BioCyc; PAER208964:G1FZ6-5470-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding; Reference proteome.
FT   CHAIN           1..90
FT                   /note="DNA-binding protein HU-alpha"
FT                   /id="PRO_0000104955"
SQ   SEQUENCE   90 AA;  9695 MW;  BCB8BCBC8868F308 CRC64;
     MRKPELAAAI AEKADLTKEQ ANRVLNALLD EITGALNRKD SVTLVGFGTF LQRHRGARTG
     KNPQTGQPVK IKASNTVAFK PGKALRDAVN