ID   DBHA_VIBPR              Reviewed;          90 AA.
AC   P28080;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=DNA-binding protein HU-alpha;
GN   Name=hupA;
OS   Vibrio proteolyticus (Aeromonas proteolytica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=671;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1508695; DOI=10.1093/nar/20.15.4092;
RA   Giladi H., Wang W.-X., Oppenheim A.B.;
RT   "Isolation and characterization of the hupA gene coding for HU of Aeromonas
RT   proteolytica.";
RL   Nucleic Acids Res. 20:4092-4092(1992).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; M96574; AAA21939.1; -; Genomic_DNA.
DR   PIR; S35438; S35438.
DR   AlphaFoldDB; P28080; -.
DR   SMR; P28080; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding.
FT   CHAIN           1..90
FT                   /note="DNA-binding protein HU-alpha"
FT                   /id="PRO_0000104995"
SQ   SEQUENCE   90 AA;  9449 MW;  5C502A9E6A8BF425 CRC64;
     MNKTQLIDFI AEKADLSKAQ AKAALEATLD GVTDALKEGD QVQLIGFGTF KVNHRAARTG
     RNPKTGAEIQ IAAANVPAFV AGKALKDAVK