DBHB_SALTY
ID DBHB_SALTY Reviewed; 90 AA.
AC P0A1R8; P05515;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=DNA-binding protein HU-beta;
DE AltName: Full=HU-1;
DE AltName: Full=NS1;
GN Name=hupB; OrderedLocusNames=STM0451;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=3043381; DOI=10.1093/nar/16.14.7196;
RA Marsh M., Hillyard D.R.;
RT "Nucleotide sequence of the HU-1 gene of Salmonella typhimurium.";
RL Nucleic Acids Res. 16:7196-7196(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC DNA to stabilize it, and thus to prevent its denaturation under extreme
CC environmental conditions.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC {ECO:0000305}.
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DR EMBL; X07844; CAA30692.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL19406.1; -; Genomic_DNA.
DR PIR; S01732; S01732.
DR RefSeq; NP_459447.1; NC_003197.2.
DR RefSeq; WP_001043544.1; NC_003197.2.
DR AlphaFoldDB; P0A1R8; -.
DR BMRB; P0A1R8; -.
DR SMR; P0A1R8; -.
DR STRING; 99287.STM0451; -.
DR PaxDb; P0A1R8; -.
DR PRIDE; P0A1R8; -.
DR EnsemblBacteria; AAL19406; AAL19406; STM0451.
DR GeneID; 1251971; -.
DR GeneID; 66754914; -.
DR KEGG; stm:STM0451; -.
DR PATRIC; fig|99287.12.peg.483; -.
DR HOGENOM; CLU_105066_3_2_6; -.
DR OMA; PAHEGIN; -.
DR PhylomeDB; P0A1R8; -.
DR BioCyc; SENT99287:STM0451-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR Gene3D; 4.10.520.10; -; 1.
DR InterPro; IPR000119; Hist_DNA-bd.
DR InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR PANTHER; PTHR33175; PTHR33175; 1.
DR Pfam; PF00216; Bac_DNA_binding; 1.
DR PRINTS; PR01727; DNABINDINGHU.
DR SMART; SM00411; BHL; 1.
DR SUPFAM; SSF47729; SSF47729; 1.
DR PROSITE; PS00045; HISTONE_LIKE; 1.
PE 3: Inferred from homology;
KW DNA condensation; DNA-binding; Reference proteome.
FT CHAIN 1..90
FT /note="DNA-binding protein HU-beta"
FT /id="PRO_0000104971"
SQ SEQUENCE 90 AA; 9240 MW; 846A3DACC622613D CRC64;
MNKSQLIEKI AAGADISKAA AGRALDAIIA SVTESLKEGD DVALVGFGTF AVKERAARTG
RNPQTGKEIT IAAAKVPSFR AGKALKDAVN
